Faculty of 1000 Biology | Current Top 10

5-Sep-2008

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	Exceptional
F1000 Factor 10.3

Hypothesis

New Finding

Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection.
Premenko-Lanier M, Moseley NB, …, Romagnoli PA, Altman JD
Nature 2008 Aug 14 454(7206):894-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Leib / Barry Rouse / Michael McChesney / Marcia Blackman / Reina Mebius

First evaluation 18 Aug 2008 | Latest evaluation 29 Aug 2008

	Exceptional
F1000 Factor 9.6

New Finding

Controversial

Dichotomous dopaminergic control of striatal synaptic plasticity.
Shen W, Flajolet M, Greengard P, Surmeier DJ
Science 2008 Aug 8 321(5890):848-51 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Xiao-Jing Wang / Michael Frank
Evaluated 19 Aug 2008

	Exceptional
F1000 Factor 8.3

Hypothesis

New Finding

A mechanism for asymmetric segregation of age during yeast budding.
Shcheprova Z, Baldi S, …, Gonnet G, Barral Y
Nature 2008 Aug 7 454(7205):728-34 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Yukiko Yamashita / Thomas Nystrom / Audrey Gasch / Karsten Weis

First evaluation 7 Aug 2008 | Latest evaluation 4 Sep 2008

	Exceptional
F1000 Factor 8.0

Confirmation

New Finding

The virophage as a unique parasite of the giant mimivirus.
La Scola B, Desnues C, …, Koonin E, Raoult D
Nature 2008 Aug 6 [abstract on PubMed] [related articles] [full text]

Selected by | Chantal Abergel / James Conway

First evaluation 13 Aug 2008 | Latest evaluation 1 Sep 2008

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy.
Wei Y, Pattingre S, …, Bassik M, Levine B
Mol Cell 2008 Jun 20 30(6):678-88 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David C Rubinsztein / Vojo Deretic
First evaluation 8 Aug 2008 | Latest evaluation 27 Aug 2008

	Must Read
F1000 Factor 6.6

New Finding

A triallelic system of S5 is a major regulator of the reproductive barrier and compatibility of indica-japonica hybrids in rice.
Chen J, Ding J, …, Xu M, Zhang Q
Proc Natl Acad Sci U S A 2008 Aug 12 105(32):11436-41 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sheila McCormick / Michael Lassner / Thomas Mitchell-Olds

First evaluation 11 Aug 2008 | Latest evaluation 3 Sep 2008

	Must Read
F1000 Factor 6.4

Confirmation

New Finding

Tech Advance

Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.
Gubbels SP, Woessner DW, …, Ricci AJ, Brigande JV
Nature 2008 Aug 27 [abstract on PubMed] [related articles] [full text]

Selected by | Harukazu Nakamura

/ Andy Groves

Evaluated 4 Sep 2008

	Must Read
F1000 Factor 6.4

Hypothesis

New Finding

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.
McGowan KA, Li JZ, …, Attardi LD, Barsh GS
Nat Genet 2008 Aug 40(8):963-70 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sandra Hofmann / Andrew Wilkie

First evaluation 8 Aug 2008 | Latest evaluation 4 Sep 2008

	Must Read
F1000 Factor 6.4

New Finding

Controversial

Neural dissociation between visual awareness and spatial attention.
Wyart V, Tallon-Baudry C
J Neurosci 2008 Mar 5 28(10):2667-79 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Petra Stoerig / Sabine Kastner

First evaluation 22 Aug 2008 | Latest evaluation 3 Sep 2008

	Must Read
F1000 Factor 6.4

New Finding

Tech Advance

Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones.
Mima J, Hickey CM, …, Jun Y, Wickner W
EMBO J 2008 Aug 6 27(15):2031-42 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Tom Stevens with Emily M Coonrod / Axel Brunger

First evaluation 11 Aug 2008 | Latest evaluation 2 Sep 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.