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Renal, Fluid & Electrolyte Physiology


 MOST VIEWED PAPERS | Renal Biology | calculated on 1 December 2008
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1
Must Read
F1000 Factor 4.8

New Finding
Refutation
 The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm.
Weavers H, Prieto-Sánchez S, …, Skaer H, Denholm B
Nature 2008 Oct 29 [abstract on PubMed] [related articles] [full text]
Selected by | David Bates / Matthew Breyer
First evaluation 7 Nov 2008 | Latest evaluation 28 Nov 2008
 
2
Recommended
F1000 Factor 3.0

Confirmation
 Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone.
Pochynyuk O, Bugaj V, …, Vallon V, Stockand JD
J Biol Chem 2008 Nov 3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 17 Nov 2008
 
3
Exceptional
F1000 Factor 8.0

New Finding
Controversial
Novel Drug Target
 Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice.
Zhou CC, Zhang Y, …, Kellems RE, Xia Y
Nat Med 2008 Aug 14(8):855-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jens Leipziger with Donna Briggs Bødtkjer / Robert Carey
First evaluation 20 Aug 2008 | Latest evaluation 24 Sep 2008
 
4
Must Read
F1000 Factor 6.0

New Finding
Tech Advance
Controversial
 Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention.
Ge Y, Bagnall AJ, …, Kotelevtsev YV, Kohan DE
Am J Physiol Renal Physiol 2008 Sep 10 [abstract on PubMed] [related articles] [full text]
Selected by | David Pollock
Evaluated 31 Oct 2008
 
5
Must Read
F1000 Factor 6.0

Tech Advance
 Rapid determination of renal filtration function using an optical ratiometric imaging approach.
Yu W, Sandoval RM, Molitoris BA
Am J Physiol Renal Physiol 2007 Jun 292(6):F1873-80 [abstract on PubMed] [related articles] [FREE full text]
Selected by | José Carlos Peña
Evaluated 14 Nov 2008
 
6
Exceptional
F1000 Factor 10.7

Hypothesis
New Finding
Tech Advance
Controversial
 Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
Crowley SD, Gurley SB, …, Le TH, Coffman TM
Proc Natl Acad Sci U S A 2006 Nov 21 103(47):17985-90 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew Breyer / Soeren Sheikh / Raymond Harris / Anna Dominiczak / Tom Lohmeier / David J Webb / Robert Carey
First evaluation 17 Nov 2006 | Latest evaluation 25 Jul 2007

 
7
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
Novel Drug Target
 TRPP2 and TRPV4 form a polymodal sensory channel complex.
Köttgen M, Buchholz B, …, Kuehn EW, Walz G
J Cell Biol 2008 Aug 11 182(3):437-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jens Leipziger with Helle A. Praetorius / Patrick Delmas
First evaluation 4 Sep 2008 | Latest evaluation 24 Sep 2008
 
8
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
 The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.
Shillingford JM, Murcia NS, …, Germino GG, Weimbs T
Proc Natl Acad Sci U S A 2006 Apr 4 103(14):5466-71 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Raymond Harris / David Cook
First evaluation 18 Apr 2006 | Latest evaluation 27 Apr 2006
 
9
Exceptional
F1000 Factor 8.0

New Finding
Novel Drug Target
 The Notch pathway in podocytes plays a role in the development of glomerular disease.
Niranjan T, Bielesz B, …, Thomas DB, Susztak K
Nat Med 2008 Mar 14(3):290-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew Breyer / Moshe Levi
First evaluation 27 Mar 2008 | Latest evaluation 12 Jun 2008

 
10
Exceptional
F1000 Factor 8.0

New Finding
 Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells.
Ichimura T, Asseldonk EJ, …, Duffield JS, Bonventre JV
J Clin Invest 2008 May 118(5):1657-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Norma A. Bobadilla / Sergio Grinstein with Gregory Fairn
First evaluation 9 Jul 2008 | Latest evaluation 30 Jul 2008


Most Viewed lists are generated every day and reflect use of F1000 Biology over the preceding 14 day period.

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