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 MOST VIEWED PAPERS | Gastrointestinal Biology | calculated on 21 November 2008
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1
Exceptional
F1000 Factor 8.3

New Finding
Novel Drug Target
 ATP drives lamina propria T(H)17 cell differentiation.
Atarashi K, Nishimura J, …, Honda K, Takeda K
Nature 2008 Oct 9 455(7214):808-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Torben Lund / Klaus Ley / Steve Ward / Ivana Novak
First evaluation 17 Oct 2008 | Latest evaluation 29 Oct 2008
 
2
Exceptional
F1000 Factor 10.3

Confirmation
Hypothesis
New Finding
Controversial
Novel Drug Target
 In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Zhou Q, Brown J, …, Rajagopal J, Melton DA
Nature 2008 Oct 2 455(7213):627-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Means / Phillip Newmark / John Mullins with L Mullins / Raghavendra Mirmira / Ray Rodgers / Ivana Novak
First evaluation 4 Sep 2008 | Latest evaluation 29 Oct 2008

 
3
Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function.
Ewaschuk JB, Diaz H, …, Looijer-van Langen M, Madsen KL
Am J Physiol Gastrointest Liver Physiol 2008 Sep 11 [abstract on PubMed] [related articles] [full text]
Selected by | Helen Raybould
Evaluated 29 Oct 2008
 
4
Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Novel Drug Target
 Transient receptor potential vanilloid-4 has a major role in visceral hypersensitivity symptoms.
Cenac N, Altier C, …, Zamponi G, Vergnolle N
Gastroenterology 2008 Sep 135(3):937-46, 946.e1-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Indu Ambudkar
Evaluated 29 Oct 2008
 
5
Must Read
F1000 Factor 4.8

New Finding
Tech Advance
 Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.
Rogers CS, Stoltz DA, …, Prather RS, Welsh MJ
Science 2008 Sep 26 321(5897):1837-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William H. Colledge / Hugo De Jonge
First evaluation 30 Sep 2008 | Latest evaluation 13 Oct 2008

 
6
Must Read
F1000 Factor 6.0

New Finding
 Reciprocal Changes in Vanilloid (TRPV1) and Endocannabinoid (CB1) Receptors Contribute to Visceral Hyperalgesia in the Water Avoidance Stressed Rat.
Hong S, Fan J, …, Li Y, Wiley JW
Gut 2008 Oct 20 [abstract on PubMed] [related articles] [full text]
Selected by | Yvette Taché
Evaluated 4 Nov 2008
 
7
Must Read
F1000 Factor 6.9

Hypothesis
New Finding
 The emergence of geometric order in proliferating metazoan epithelia.
Gibson MC, Patel AB, Nagpal R, Perrimon N
Nature 2006 Aug 31 442(7106):1038-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jennifer Zallen / Laura Johnston / Thomas Lecuit / Ken Irvine / David Alpers
First evaluation 31 Aug 2006 | Latest evaluation 7 Nov 2006
 
8
Must Read
F1000 Factor 6.5

Confirmation
Hypothesis
New Finding
Novel Drug Target
 Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth.
Lee JH, Karamychev VN, …, Weimer B, O'Sullivan DJ
BMC Genomics 2008 9:247 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Claire Shearman / Frank Robb / David Alpers
First evaluation 2 Jun 2008 | Latest evaluation 11 Aug 2008
 
9
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
 Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.
Lin J, Yang R, …, Newgard CB, Spiegelman BM
Cell 2005 Jan 28 120(2):261-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Webb / Michael Muller
First evaluation 22 Mar 2005 | Latest evaluation 8 Apr 2005
 
10
Recommended
F1000 Factor 3.0

New Finding
 Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury.
Pull SL, Doherty JM, …, Gordon JI, Stappenbeck TS
Proc Natl Acad Sci U S A 2005 Jan 4 102(1):99-104 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lora Hooper
Evaluated 5 May 2005

Most Viewed lists are generated every day and reflect use of F1000 Biology over the preceding 14 day period.

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