Faculty of 1000 Biology | Most-viewed Top 10

21-Nov-2008

Top 10s

Cancer Biology

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Cancer Therapeutics

Cell Growth & Division

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	Exceptional
F1000 Factor 9.0

Hypothesis

New Finding

Tech Advance

Global reorganization of replication domains during embryonic stem cell differentiation.
Hiratani I, Ryba T, …, Schübeler D, Gilbert DM
PLoS Biol 2008 Oct 7 6(10):e245 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Joel Huberman
Evaluated 11 Nov 2008

	Must Read
F1000 Factor 6.6

Hypothesis

New Finding

HARP is an ATP-driven annealing helicase.
Yusufzai T, Kadonaga JT
Science 2008 Oct 31 322(5902):748-50 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Michael Botchan / Lucio Comai

/ Jessica Downs

First evaluation 13 Nov 2008 | Latest evaluation 17 Nov 2008

	Must Read
F1000 Factor 6.8

Confirmation

Hypothesis

New Finding

Controversial

CTLA-4 control over Foxp3+ regulatory T cell function.
Wing K, Onishi Y, …, Nomura T, Sakaguchi S
Science 2008 Oct 10 322(5899):271-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Richard Williams / Kenneth Tung with Alberta Paul / Jay Berzofsky / Arthur Hurwitz / Kendall Smith

First evaluation 22 Oct 2008 | Latest evaluation 20 Nov 2008

	Exceptional
F1000 Factor 12.3

New Finding

Tech Advance

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system.
Livet J, Weissman TA, …, Sanes JR, Lichtman JW
Nature 2007 Nov 1 450(7166):56-62 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kees Jalink / Alain Ghysen / Jonathan Sweedler / Liqun Luo / Catherine Krull / Markus Ruegg / Stanley Appel / David P. Wolfer / Andy Groves / Bruce Cumming / Guoping Feng / Edvard I. Moser / Etienne Joly / Martine Roussel
First evaluation 8 Nov 2007 | Latest evaluation 22 Jan 2008

	Recommended
F1000 Factor 3.0

Hypothesis

New Finding

Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation.
Shalem O, Dahan O, …, Segal E, Pilpel Y
Mol Syst Biol 2008 4:223 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Jurg Bahler
Evaluated 12 Nov 2008

	Must Read
F1000 Factor 6.0

Confirmation

Hypothesis

New Finding

Redundant mechanisms recruit actin into the contractile ring in silkworm spermatocytes.
Chen W, Foss M, Tseng KF, Zhang D
PLoS Biol 2008 Sep 2 6(9):e209 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Dannel McCollum
Evaluated 11 Nov 2008

	Must Read
F1000 Factor 6.5

Hypothesis

New Finding

A network of nuclear envelope membrane proteins linking centromeres to microtubules.
King MC, Drivas TG, Blobel G
Cell 2008 Aug 8 134(3):427-38 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Dannel McCollum / Stephen Doxsey / Harald Herrmann with Monika Zwerger
First evaluation 19 Sep 2008 | Latest evaluation 10 Nov 2008

	Must Read
F1000 Factor 6.0

Hypothesis

New Finding

Promoter-driven splicing regulation in fission yeast.
Moldón A, Malapeira J, …, Seidel C, Ayté J
Nature 2008 Oct 16 455(7215):997-1000 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Christopher McInerny
Evaluated 28 Oct 2008

	Exceptional
F1000 Factor 9.0

New Finding

Tech Advance

Homologous recombination in real time: DNA strand exchange by RecA.
van der Heijden T, Modesti M, …, Wyman C, Dekker C
Mol Cell 2008 May 23 30(4):530-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Johannes Walter

Evaluated 20 Nov 2008

	Recommended
F1000 Factor 3.0

Confirmation

New Finding

Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation.
Ruiz EJ, Hunt T, Nebreda AR
Mol Cell 2008 Oct 24 32(2):210-20 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Robert Fisher with Karl Merrick
Evaluated 11 Nov 2008

Most Viewed lists are generated every day and reflect use of F1000 Biology over the preceding 14 day period.