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Allergy & Hypersensitivity
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Genetics of the Immune System
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Related Sections
Cellular Microbiology & Pathogenesis
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 MOST VIEWED PAPERS | Immunology | calculated on 21 November 2008
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1
Exceptional
F1000 Factor 10.3

Hypothesis
New Finding
Tech Advance
Novel Drug Target
 Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
Wen L, Ley RE, …, Gordon JI, Chervonsky AV
Nature 2008 Oct 23 455(7216):1109-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mauro Teixeira / David Serreze / Antony Basten with Pablo Silveira / Torben Lund / Peter Van Endert / Aniko Naray-Fejes-Toth
First evaluation 3 Oct 2008 | Latest evaluation 29 Oct 2008

 
2
Must Read
F1000 Factor 6.8

Confirmation
Hypothesis
New Finding
Controversial
 CTLA-4 control over Foxp3+ regulatory T cell function.
Wing K, Onishi Y, …, Nomura T, Sakaguchi S
Science 2008 Oct 10 322(5899):271-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Williams / Kenneth Tung with Alberta Paul / Jay Berzofsky / Arthur Hurwitz / Kendall Smith
First evaluation 22 Oct 2008 | Latest evaluation 20 Nov 2008

 
3
Must Read
F1000 Factor 6.0

New Finding
Controversial
 IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma.
Song C, Luo L, …, Huang B, Feng ZH
J Immunol 2008 Nov 1 181(9):6117-24 [abstract on PubMed] [related articles] [order article]
Selected by | Dan Conrad
Evaluated 11 Nov 2008
 
4
Must Read
F1000 Factor 6.0

New Finding
 A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity.
Cella M, Fuchs A, …, Mills JC, Colonna M
Nature 2008 Nov 2 [abstract on PubMed] [related articles] [full text]
Selected by | Mauro Teixeira
Evaluated 10 Nov 2008
 
5
Must Read
F1000 Factor 6.0

New Finding
 CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming.
Martín-Fontecha A, Baumjohann D, …, Lanzavecchia A, Sallusto F
J Exp Med 2008 Oct 27 205(11):2561-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Linda Bradley
Evaluated 14 Nov 2008
 
6
Exceptional
F1000 Factor 8.0

New Finding
 Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine.
Ivanov II, Frutos Rde L, …, Finlay BB, Littman DR
Cell Host Microbe 2008 Oct 16 4(4):337-49 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Klaus Ley / David Underhill
First evaluation 24 Oct 2008 | Latest evaluation 30 Oct 2008
 
7
Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.
Rubic T, Lametschwandtner G, …, Rot A, Carballido JM
Nat Immunol 2008 Nov 9(11):1261-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mauro Teixeira
Evaluated 10 Nov 2008
 
8
Exceptional
F1000 Factor 8.3

New Finding
Novel Drug Target
 ATP drives lamina propria T(H)17 cell differentiation.
Atarashi K, Nishimura J, …, Honda K, Takeda K
Nature 2008 Oct 9 455(7214):808-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Torben Lund / Klaus Ley / Steve Ward / Ivana Novak
First evaluation 17 Oct 2008 | Latest evaluation 29 Oct 2008
 
9
Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events.
Cavassani KA, Ishii M, …, Hogaboam CM, Kunkel SL
J Exp Med 2008 Oct 27 205(11):2609-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Takeshi Tsubata
Evaluated 4 Nov 2008

 
10
Exceptional
F1000 Factor 12.3

New Finding
Tech Advance
 Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system.
Livet J, Weissman TA, …, Sanes JR, Lichtman JW
Nature 2007 Nov 1 450(7166):56-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kees Jalink / Alain Ghysen / Jonathan Sweedler / Liqun Luo / Catherine Krull / Markus Ruegg / Stanley Appel / David P. Wolfer / Andy Groves / Bruce Cumming / Guoping Feng / Edvard I. Moser / Etienne Joly / Martine Roussel
First evaluation 8 Nov 2007 | Latest evaluation 22 Jan 2008

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