Faculty of 1000 Biology | Most-viewed Top 10

21-Nov-2008

Top 10s

Molecular Medicine

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Antimicrobial Agents

Autoimmunity

Cancer Therapeutics

Cardiovascular Pharmacology

Cardiovascular Physiology/Circulation

Cell Growth & Division

Drug Discovery & Design

Endocrine & Metabolic Pharmacology

Endocrinology

Gastrointestinal Pharmacology

Gastrointestinal Physiology

Genito-Urinary & Reproductive Pharmacology

Immunomodulation

Immunopharmacology & Hematologic Pharmacology

Integrative Physiology

Medical Genetics

Medical Microbiology

Molecular Pharmacology

Muscle & Connective Tissue

Musculoskeletal & Dermatologic Pharmacology

Neural Homeostasis

Neurobiology of Disease & Regeneration

Neuropharmacology & Psychopharmacology

Pharmacogenomics

Pharmacokinetics & Drug Delivery

Physiogenomics

Renal, Fluid & Electrolyte Physiology

Reproductive Physiology

Respiratory physiology

Stem Cells & Regeneration

Toxicology

email [Help]

	Exceptional
F1000 Factor 9.0

Hypothesis

New Finding

Tech Advance

Global reorganization of replication domains during embryonic stem cell differentiation.
Hiratani I, Ryba T, …, Schübeler D, Gilbert DM
PLoS Biol 2008 Oct 7 6(10):e245 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Joel Huberman
Evaluated 11 Nov 2008

	Exceptional
F1000 Factor 8.2

Hypothesis

New Finding

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.
Wirtz-Peitz F, Nishimura T, Knoblich JA
Cell 2008 Oct 3 135(1):161-73 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Cheng-Yu Lee / Yukiko Yamashita / Valeri Vasioukhin
First evaluation 27 Oct 2008 | Latest evaluation 7 Nov 2008

	Exceptional
F1000 Factor 10.3

Hypothesis

New Finding

Tech Advance

Novel Drug Target

Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
Wen L, Ley RE, …, Gordon JI, Chervonsky AV
Nature 2008 Oct 23 455(7216):1109-13 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Mauro Teixeira / David Serreze / Antony Basten with Pablo Silveira / Torben Lund / Peter Van Endert / Aniko Naray-Fejes-Toth
First evaluation 3 Oct 2008 | Latest evaluation 29 Oct 2008

	Exceptional
F1000 Factor 9.0

Hypothesis

Controversial

Philip Morris's health information web site appears responsible but undermines public health.
Smith EA, Malone RE
Public Health Nurs 2008 Nov-Dec 25(6):554-64 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Neil Grunberg
Evaluated 10 Nov 2008

	Must Read
F1000 Factor 6.6

Hypothesis

New Finding

HARP is an ATP-driven annealing helicase.
Yusufzai T, Kadonaga JT
Science 2008 Oct 31 322(5902):748-50 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Michael Botchan / Lucio Comai

/ Jessica Downs

First evaluation 13 Nov 2008 | Latest evaluation 17 Nov 2008

	Must Read
F1000 Factor 6.8

Confirmation

Hypothesis

New Finding

Controversial

CTLA-4 control over Foxp3+ regulatory T cell function.
Wing K, Onishi Y, …, Nomura T, Sakaguchi S
Science 2008 Oct 10 322(5899):271-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Richard Williams / Kenneth Tung with Alberta Paul / Jay Berzofsky / Arthur Hurwitz / Kendall Smith

First evaluation 22 Oct 2008 | Latest evaluation 20 Nov 2008

	Must Read
F1000 Factor 6.0

Hypothesis

New Finding

Delivery of AMPA receptors to perisynaptic sites precedes the full expression of long-term potentiation.
Yang Y, Wang XB, Frerking M, Zhou Q
Proc Natl Acad Sci U S A 2008 Aug 12 105(32):11388-93 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Michael Ehlers
Evaluated 6 Nov 2008

	Exceptional
F1000 Factor 9.0

New Finding

Controversial

Refutation

Increased cognitive functioning in symptomatic Huntington's disease as revealed by behavioral and event-related potential indices of auditory sensory memory and attention.
Beste C, Saft C, Güntürkün O, Falkenstein M
J Neurosci 2008 Nov 5 28(45):11695-702 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Jerry Buccafusco
Evaluated 12 Nov 2008

	Must Read
F1000 Factor 6.0

Hypothesis

New Finding

Conditioning of stimuli with nonzero initial value.
Rescorla RA
J Exp Psychol Anim Behav Process 2008 Jul 34(3):315-23 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Terry Davidson
Evaluated 11 Nov 2008

	Must Read
F1000 Factor 6.0

New Finding

Tech Advance

Anatomical profiling of G protein-coupled receptor expression.
Regard JB, Sato IT, Coughlin SR
Cell 2008 Oct 31 135(3):561-71 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Soeren Sheikh

Evaluated 14 Nov 2008

Most Viewed lists are generated every day and reflect use of F1000 Biology over the preceding 14 day period.