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Biomacromolecule-Ligand Interactions
Cell Signalling & Trafficking Structures
Experimental Biophysical Methods
Macromolecular Assemblies & Machines
Membrane Proteins & Energy Transduction
Protein Folding
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Biocatalysis
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 HIDDEN JEWELS | Structural Biology | calculated on 21 November 2008
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1
Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
Crystal Structure of a Ten-Amino Acid Protein.
Honda S, Akiba T, …, Odahara T, Harata K
J Am Chem Soc 2008 Oct 25 0 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Torleif Härd
Evaluated 12 Nov 2008
 
2
Exceptional
F1000 Factor 9.0

Tech Advance
Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules.
Hodis E, Prilusky J, …, Moult J, Sussman JL
Genome Biol 2008 Aug 3 9(8):R121 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Burkhard Rost
Evaluated 29 Oct 2008
 
3
Must Read
F1000 Factor 6.0

New Finding
Tech Advance
The membrane potential and its representation by a constant electric field in computer simulations.
Roux B
Biophys J 2008 Nov 1 95(9):4205-16 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nathan Baker with Marcelo Marucho
Evaluated 5 Nov 2008
 
4
Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
A specificity map for the PDZ domain family.
Tonikian R, Zhang Y, …, Bader GD, Sidhu SS
PLoS Biol 2008 Sep 30 6(9):e239 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Willson
Evaluated 22 Oct 2008
 
5
Recommended
F1000 Factor 3.0

Tech Advance
A quantitative coarse-grain model for lipid bilayers.
Orsi M, Haubertin DY, Sanderson WE, Essex JW
J Phys Chem B 2008 Jan 24 112(3):802-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Qiang Cui
Evaluated 4 Nov 2008
 
6
Recommended
F1000 Factor 3.0

New Finding
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response.
Morin I, Ngo HP, …, Morrice N, Lydall D
EMBO J 2008 Sep 17 27(18):2400-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lorraine Symington
Evaluated 4 Nov 2008
 
7
Recommended
F1000 Factor 3.0

New Finding
Human DNA polymerase iota protects cells against oxidative stress.
Petta TB, Nakajima S, …, Yasui A, Kannouche P
EMBO J 2008 Nov 5 27(21):2883-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Lehmann
Evaluated 13 Nov 2008
 
8
Must Read
F1000 Factor 6.0

Hypothesis
New Finding
The effect of cholesterol on short- and long-chain monounsaturated lipid bilayers as determined by molecular dynamics simulations and X-ray scattering.
Kucerka N, Perlmutter JD, …, Katsaras J, Sachs JN
Biophys J 2008 Sep 15 95(6):2792-805 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nathan Baker with Brett Olsen
Evaluated 4 Nov 2008
 
9
Exceptional
F1000 Factor 9.0

New Finding
Refutation
Novel Drug Target
Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.
Boshoff HI, Xu X, …, Williams KJ, Barry CE
J Biol Chem 2008 Jul 11 283(28):19329-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Squire Booker
Evaluated 27 Oct 2008
 
10
Must Read
F1000 Factor 6.0

Hypothesis
Refutation
Novel Drug Target
Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.
Baxter NJ, Blackburn GM, …, Wemmer DE, Waltho JP
J Am Chem Soc 2008 Mar 26 130(12):3952-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arieh Warshel with Shina Caroline Lynn Kamerlin
Evaluated 13 Nov 2008

Hidden Jewels Top 10 lists are generated every day and comprise only papers published in less widely read journals (the grouping of which is the same for all Faculties; therefore, whilst some of these journals may be considered 'high profile' in their immediate Faculty, they are included in the Hidden Jewels lists because they probably will not be so obvious to people outside that specific Faculty). The Hidden Jewels list of papers is ordered by the number of times a paper's evaluation(s) has been viewed over the past 14 days.


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