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Control of Gene Expression
Nuclear Structure & Function


 HIDDEN JEWELS | Molecular Biology | calculated on 21 November 2008
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1
Recommended
F1000 Factor 3.0

Hypothesis
Controversial
Structure and dynamics of interphase chromosomes.
Rosa A, Everaers R
PLoS Comput Biol 2008 4(8):e1000153 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Shaw
Evaluated 10 Nov 2008
 
2
Recommended
F1000 Factor 3.0

New Finding
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.
Brown JM, Green J, …, Iborra FJ, Buckle VJ
J Cell Biol 2008 Sep 22 182(6):1083-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Shaw
Evaluated 18 Nov 2008
 
3
Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways.
Kwapisz M, Wery M, …, Thuriaux P, Lacroute F
EMBO J 2008 Sep 17 27(18):2411-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jesper Svejstrup with Ozan Aygun
Evaluated 11 Nov 2008
 
4
Recommended
F1000 Factor 3.0

New Finding
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
Sheaffer KL, Updike DL, Mango SE
Curr Biol 2008 Sep 23 18(18):1355-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Proud
Evaluated 12 Nov 2008
 
5
Must Read
F1000 Factor 6.0

New Finding
Alternative mRNA polyadenylation can potentially affect detection of gene expression by affymetrix genechip arrays.
D'mello V, Lee JY, MacDonald CC, Tian B
Appl Bioinformatics 2006 5(4):249-53 [abstract on PubMed] [related articles] [order article]
Selected by | Samuel Gunderson
Evaluated 11 Apr 2007
 
6
Recommended
F1000 Factor 3.0

Confirmation
New Finding
PPAR{gamma} and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.
Lefterova MI, Zhang Y, …, Liu XS, Lazar MA
Genes Dev 2008 Nov 1 22(21):2941-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D. Sharrocks
Evaluated 18 Nov 2008
 
7
Recommended
F1000 Factor 3.0

Confirmation
Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3.
Mohibullah N, Hahn S
Genes Dev 2008 Nov 1 22(21):2994-3006 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tony Weil
Evaluated 11 Nov 2008
 
8
Recommended
F1000 Factor 3.0

New Finding
CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response.
Filippi S, Latini P, …, Egly JM, Proietti-De-Santis L
EMBO J 2008 Oct 8 27(19):2545-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 27 Oct 2008
 
9
Recommended
F1000 Factor 3.0

New Finding
Whi3, a Developmental Regulator of Budding Yeast, Binds a Large Set of mRNAs Functionally Related to the Endoplasmic Reticulum.
Colomina N, Ferrezuelo F, …, Aldea M, Garí E
J Biol Chem 2008 Oct 17 283(42):28670-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roy Long
Evaluated 29 Oct 2008
 
10
Recommended
F1000 Factor 3.0

New Finding
Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.
Kanadia RN, Clark VE, …, Trimarchi JM, Cepko CL
Development 2008 Dec 135(23):3923-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Reinhard Luehrmann
Evaluated 20 Nov 2008

Hidden Jewels Top 10 lists are generated every day and comprise only papers published in less widely read journals (the grouping of which is the same for all Faculties; therefore, whilst some of these journals may be considered 'high profile' in their immediate Faculty, they are included in the Hidden Jewels lists because they probably will not be so obvious to people outside that specific Faculty). The Hidden Jewels list of papers is ordered by the number of times a paper's evaluation(s) has been viewed over the past 14 days.


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