Faculty of 1000 Biology | All Time Top 10

1-Dec-2008

Top 10s

Developmental Biology

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Developmental Evolution

Developmental Molecular Mechanisms

Morphogenesis & Cell Biology

Pattern Formation

Stem Cells & Regeneration

Related Sections

Leukocyte Development

Microbial Growth & Development

Neurodevelopment

Plant Growth & Development

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	Exceptional
F1000 Factor 14.5

Hypothesis

New Finding

Controversial

Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis.
Lolle SJ, Victor JL, Young JM, Pruitt RE
Nature 2005 Mar 24 434(7032):505-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Frank Lyko / Shigeru Iida / Kay Schneitz / Judy Wall / Marjori Matzke / James Carrington / Jose Luis Riechmann / Christian Hardtke / John Bowman / James Hu / Caren Chang / Venkatesan Sundaresan / Philip Benfey / Stephan Beck / Magnus Nordborg / Neelima Sinha / Martin Parniske / Elena Alvarez-Buylla / Elizabeth Kellogg / Elizabeth Hood
Dissenters | Alejandro Sanchez-Alvarado
First evaluation 24 Mar 2005 | Latest evaluation 24 May 2005

	Exceptional
F1000 Factor 12.3

New Finding

Tech Advance

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system.
Livet J, Weissman TA, …, Sanes JR, Lichtman JW
Nature 2007 Nov 1 450(7166):56-62 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kees Jalink / Alain Ghysen / Jonathan Sweedler / Liqun Luo / Catherine Krull / Markus Ruegg / Stanley Appel / David P. Wolfer / Andy Groves / Bruce Cumming / Guoping Feng / Edvard I. Moser / Etienne Joly / Martine Roussel
First evaluation 8 Nov 2007 | Latest evaluation 22 Jan 2008

	Exceptional
F1000 Factor 11.7

Hypothesis

New Finding

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.
Iijima M, Devreotes P
Cell 2002 May 31 109(5):599-610 [abstract on PubMed] [related articles] [order article]

Selected by | Silvia Arber / Silvio Gutkind / Steve Ward / Bruce Conklin / Phillip Hawkins / Jeffrey Axelrod / Henry R. Bourne / David Lambright / Anna Huttenlocher / Andreas Wodarz / Richard Gomer / Gerald Weeks
First evaluation 5 Jun 2002 | Latest evaluation 13 Aug 2002

	Exceptional
F1000 Factor 11.6

Hypothesis

New Finding

Controversial

Deconstructing the cadherin-catenin-actin complex.
Yamada S, Pokutta S, …, Weis WI, Nelson WJ
Cell 2005 Dec 2 123(5):889-901 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Rong Li / Kenneth Yamada / Mariann Bienz / Frans Van Roy / William A Muller / Michel Labouesse / Thomas Lecuit / Kathleen J. Green / Carien Niessen / Jeff Hardin
First evaluation 6 Dec 2005 | Latest evaluation 11 Aug 2006

	Exceptional
F1000 Factor 11.2

Hypothesis

New Finding

Controversial

Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.
Drees F, Pokutta S, …, Nelson WJ, Weis WI
Cell 2005 Dec 2 123(5):903-15 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Rong Li / Kenneth Yamada / Mariann Bienz / Frans Van Roy / William A Muller / Michel Labouesse / Marie-France Carlier / Kathleen J. Green / Carien Niessen
First evaluation 6 Dec 2005 | Latest evaluation 3 May 2006

	Exceptional
F1000 Factor 11.1

Hypothesis

New Finding

Tech Advance

Matrix elasticity directs stem cell lineage specification.
Engler AJ, Sen S, Sweeney HL, Discher DE
Cell 2006 Aug 25 126(4):677-89 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kenneth Yamada / Ray Rodgers / Carol Otey / Paul Bornstein / Avri Ben-Ze'ev / Michel Labouesse / Thomas Egelhoff / Deborah Andrew / Amy Wagers
First evaluation 30 Aug 2006 | Latest evaluation 3 Sep 2007

	Exceptional
F1000 Factor 11.1

Confirmation

Hypothesis

New Finding

Surface mechanics mediate pattern formation in the developing retina.
Hayashi T, Carthew RW
Nature 2004 Oct 7 431(7009):647-52 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Deborah Leckband / Talila Volk / Marta Llimargas / Buzz Baum / Jennifer Fletcher / Jeffrey Axelrod / Carien Niessen / Ross Cagan / David Bilder
First evaluation 13 Oct 2004 | Latest evaluation 31 Mar 2005

	Exceptional
F1000 Factor 11.1

Hypothesis

New Finding

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis.
Funamoto S, Meili R, …, Parry L, Firtel RA
Cell 2002 May 31 109(5):611-23 [abstract on PubMed] [related articles] [order article]

Selected by | Silvio Gutkind / Steve Ward / Bruce Conklin / Phillip Hawkins / Jeffrey Axelrod / Henry R. Bourne / David Lambright / Andreas Wodarz / Gerald Weeks
First evaluation 19 Jun 2002 | Latest evaluation 13 Aug 2002

	Exceptional
F1000 Factor 11.0

New Finding

Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles.
Colosimo PF, Hosemann KE, …, Schluter D, Kingsley DM
Science 2005 Mar 25 307(5717):1928-33 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Detlef Weigel / Mohamed Noor / Patricia Simpson / Tony Long / Richard Harrison / Trudy Mackay / Molly Przeworski / Magnus Nordborg
First evaluation 6 Apr 2005 | Latest evaluation 16 Jun 2005

	Exceptional
F1000 Factor 11.0

Hypothesis

New Finding

Tech Advance

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity.
Ozdamar B, Bose R, …, Zhang Y, Wrana JL
Science 2005 Mar 11 307(5715):1603-9 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Victor Thannickal / Keith Mostov / David Wotton / David Bilder / Valeri Vasioukhin / Filippo Giancotti / Alfonso Martinez Arias / Andreas Wodarz / Francisco Sanchez-Madrid
First evaluation 16 Mar 2005 | Latest evaluation 3 Jun 2005

All Time Top 10s are generated every day using papers added to F1000 Biology since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.