Faculty of 1000 Biology | All Time Top 10

7-Oct-2008

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ALL OF BIOLOGY

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	Exceptional
F1000 Factor 14.5

Hypothesis

New Finding

Controversial

Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis.
Lolle SJ, Victor JL, Young JM, Pruitt RE
Nature 2005 Mar 24 434(7032):505-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Frank Lyko / Shigeru Iida / Kay Schneitz / Judy Wall / Marjori Matzke / James Carrington / Jose Luis Riechmann / Christian Hardtke / John Bowman / James Hu / Caren Chang / Venkatesan Sundaresan / Philip Benfey / Stephan Beck / Magnus Nordborg / Neelima Sinha / Martin Parniske / Elena Alvarez-Buylla / Elizabeth Kellogg / Elizabeth Hood
Dissenters | Alejandro Sanchez-Alvarado
First evaluation 24 Mar 2005 | Latest evaluation 24 May 2005

	Exceptional
F1000 Factor 12.8

Hypothesis

New Finding

Control of gene expression by a natural metabolite-responsive ribozyme.
Winkler WC, Nahvi A, …, Collins JA, Breaker RR
Nature 2004 Mar 18 428(6980):281-6 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David M.J. Lilley / Richard Maraia / Samuel Butcher / Eric Westhof / Peter Unrau / Scott K. Silverman / Fritz Eckstein / Burckhard Seelig / Andrew D. Sharrocks / Janet Morrow / Andres Jaschke / John Burke / Reinhard Luehrmann
First evaluation 18 Mar 2004 | Latest evaluation 17 May 2004

	Exceptional
F1000 Factor 12.4

Hypothesis

New Finding

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.
Chang JT, Palanivel VR, …, Weninger W, Reiner SL
Science 2007 Mar 23 315(5819):1687-91 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | George Yap / Toshinori Nakayama / Richard Locksley / Etienne Joly / Torben Lund / Christian Engwerda / Stephen Doxsey / Clifford Harding / Leo Lefrancois / Shiv Pillai / Rong Li / Dale Umetsu / Michael Dustin / Francisco Sanchez-Madrid
First evaluation 14 Mar 2007 | Latest evaluation 3 Mar 2008

	Exceptional
F1000 Factor 12.4

Confirmation

New Finding

Tech Advance

Functional organization of the yeast proteome by systematic analysis of protein complexes.
Gavin AC, Bösche M, …, Neubauer G, Superti-Furga G
Nature 2002 Jan 10 415(6868):141-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Michael Blatt / Kiyoshi Nagai / Sue Goo Rhee / Stephen Jackson / Steven Gygi / Guoping Feng / Mark Nelson / Rolf Apweiler / Marilyn Parsons / Miguel Penalva / Marie-Laure Yaspo / Ron Milligan / Michael Kiebler
First evaluation 18 Jan 2002 | Latest evaluation 24 Jul 2007

	Exceptional
F1000 Factor 12.4

Confirmation

Hypothesis

New Finding

Tech Advance

Controversial

X-ray structure of a protein-conducting channel.
Van den Berg B, Clemons WM, …, Harrison SC, Rapoport TA
Nature 2004 Jan 1 427(6969):36-44 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Koreaki Ito / Karin Romisch / Jia-huai Wang / Stephen White / Tracy Palmer / Davis Ng / Senyon Choe / Ada Yonath / Kiyoshi Nagai / Manfred Schliwa / Bernd Bukau / Douglas Freymann
First evaluation 22 Dec 2003 | Latest evaluation 2 Mar 2004

	Exceptional
F1000 Factor 12.3

New Finding

Tech Advance

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system.
Livet J, Weissman TA, …, Sanes JR, Lichtman JW
Nature 2007 Nov 1 450(7166):56-62 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kees Jalink / Alain Ghysen / Jonathan Sweedler / Liqun Luo / Catherine Krull / Markus Ruegg / Stanley Appel / David P. Wolfer / Andy Groves / Bruce Cumming / Guoping Feng / Edvard I. Moser / Etienne Joly / Martine Roussel
First evaluation 8 Nov 2007 | Latest evaluation 22 Jan 2008

	Exceptional
F1000 Factor 12.1

Hypothesis

New Finding

Tech Advance

Restoring function in exhausted CD8 T cells during chronic viral infection.
Barber DL, Wherry EJ, …, Freeman GJ, Ahmed R
Nature 2006 Feb 9 439(7077):682-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Barry Rouse / Etienne Joly / Christian Engwerda / Nicholas Restifo / Allan Zajac / Linda Bradley / Jonathan Green / Lieping Chen / Luis J. Montaner / Arthur Hurwitz / Grant McFadden / Matthias von Herrath / Scott Gray-Owen
First evaluation 10 Jan 2006 | Latest evaluation 12 Jul 2006

	Exceptional
F1000 Factor 11.7

Confirmation

Hypothesis

New Finding

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
Shi Y, Lan F, …, Casero RA, Shi Y
Cell 2004 Dec 29 119(7):941-53 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Steven Henikoff / Thomas Jenuwein / Chris Sander / Winship Herr / Dinah Singer / Robert Dutnall / Eric Selker / Frank Lyko / Daniel Reines / Benoit Coulombe / Robin Allshire
First evaluation 21 Dec 2004 | Latest evaluation 3 Feb 2005

	Exceptional
F1000 Factor 11.7

Hypothesis

New Finding

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.
Iijima M, Devreotes P
Cell 2002 May 31 109(5):599-610 [abstract on PubMed] [related articles] [order article]

Selected by | Silvia Arber / Silvio Gutkind / Steve Ward / Bruce Conklin / Phillip Hawkins / Jeffrey Axelrod / Henry R. Bourne / David Lambright / Anna Huttenlocher / Andreas Wodarz / Richard Gomer / Gerald Weeks
First evaluation 5 Jun 2002 | Latest evaluation 13 Aug 2002

	Exceptional
F1000 Factor 11.6

Hypothesis

New Finding

Controversial

Deconstructing the cadherin-catenin-actin complex.
Yamada S, Pokutta S, …, Weis WI, Nelson WJ
Cell 2005 Dec 2 123(5):889-901 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Rong Li / Kenneth Yamada / Mariann Bienz / Frans Van Roy / William A Muller / Michel Labouesse / Thomas Lecuit / Kathleen J. Green / Carien Niessen / Jeff Hardin
First evaluation 6 Dec 2005 | Latest evaluation 11 Aug 2006

All Time Top 10s are generated every day using papers added to F1000 Biology since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.