Faculty of 1000 Biology | Current Top 10

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Cardiovascular Biology

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Cardiovascular Pharmacology

Cardiovascular Physiology/Circulation

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	Must Read
F1000 Factor 6.4

Hypothesis

New Finding

Controversial

The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity.
Gentile S, Martin N, …, Erxleben C, Armstrong DL
Proc Natl Acad Sci U S A 2008 Sep 23 105(38):14704-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Stanley Nattel / Hugues Abriel with Jean-Sébastien Rougier

First evaluation 25 Sep 2008 | Latest evaluation 18 Nov 2008

	Must Read
F1000 Factor 4.8

Hypothesis

New Finding

Imbalance of angiotensin type 1 receptor and angiotensin II type 2 receptor in the rostral ventrolateral medulla: potential mechanism for sympathetic overactivity in heart failure.
Gao L, Wang WZ, Wang W, Zucker IH
Hypertension 2008 Oct 52(4):708-14 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Tom Lohmeier / Robert Widdop
First evaluation 3 Oct 2008 | Latest evaluation 23 Oct 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.