Faculty of 1000 Biology | Current Top 10

Top 10s

Physiology

Current Top 10

All Time Top 10

Most-viewed Top 10

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Sections Covered

Cardiovascular Physiology/Circulation

Endocrinology

Gastrointestinal Physiology

Integrative Physiology

Muscle & Connective Tissue

Neural Homeostasis

Physiogenomics

Renal, Fluid & Electrolyte Physiology

Reproductive Physiology

Respiratory physiology

Related Sections

Behavioural Neuroscience

Cell Signalling

Cognitive Neuroscience

Genomics

Immune Response

Immunity to Infections

Medical Genetics

Membranes & Sorting

Morphogenesis & Cell Biology

Motor Systems

Neurodevelopment

Neuronal Signalling Mechanisms

Pattern Formation

Sensory Systems

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	Exceptional
F1000 Factor 9.6

New Finding

Astroglial metabolic networks sustain hippocampal synaptic transmission.
Rouach N, Koulakoff A, …, Willecke K, Giaume C
Science 2008 Dec 5 322(5907):1551-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Arturo Alvarez-Buylla

/ Achim Peters

First evaluation 2 Jan 2009 | Latest evaluation 7 Jan 2009

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Genomic anatomy of the hippocampus.
Thompson CL, Pathak SD, …, Hawrylycz MJ, Lein ES
Neuron 2008 Dec 26 60(6):1010-21 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Edvard I. Moser

/ Luis de Lecea

First evaluation 7 Jan 2009 | Latest evaluation 8 Jan 2009

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Tech Advance

Novel Drug Target

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice.
Louvet C, Szot GL, …, Weiss A, Bluestone JA
Proc Natl Acad Sci U S A 2008 Dec 2 105(48):18895-900 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Steven A. Rosenzweig / Daniel Flynn
First evaluation 8 Dec 2008 | Latest evaluation 12 Dec 2008

	Must Read
F1000 Factor 4.8

Confirmation

New Finding

Tech Advance

Controversial

A functional genetic link between distinct developmental language disorders.
Vernes SC, Newbury DF, …, Monaco AP, Fisher SE
N Engl J Med 2008 Nov 27 359(22):2337-45 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Isaac Kohane / Sue Malcolm with Sayeda Abu-Amero

First evaluation 21 Nov 2008 | Latest evaluation 9 Jan 2009

	Must Read
F1000 Factor 4.8

New Finding

Novel Drug Target

The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.
Sapieha P, Sirinyan M, …, Sennlaub F, Chemtob S
Nat Med 2008 Oct 14(10):1067-76 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Raymond Harris / Andrius Kazlauskas

First evaluation 17 Nov 2008 | Latest evaluation 7 Jan 2009

	Must Read
F1000 Factor 4.8

Hypothesis

New Finding

TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.
Topaloglu AK, Reimann F, …, O'Rahilly S, Semple RK
Nat Genet 2008 Dec 11 [abstract on PubMed] [related articles] [full text]

Selected by | Tony Plant / Allan Herbison
First evaluation 18 Dec 2008 | Latest evaluation 22 Dec 2008

	Recommended
F1000 Factor 3.2

Hypothesis

New Finding

Tech Advance

Controversial

Energy uptake and allocation during ontogeny.
Hou C, Zuo W, …, Brown JH, West GB
Science 2008 Oct 31 322(5902):736-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Raymond Mejia / Susan Akana
First evaluation 25 Nov 2008 | Latest evaluation 17 Dec 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.