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Applied Microbiology
Cellular Microbiology & Pathogenesis
Environmental Microbiology
Medical Microbiology
Microbial Evolution & Genomics
Microbial Growth & Development
Microbial Physiology & Metabolism
Parasitology
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Antimicrobial Agents
Immunity to Infections
Innate Immunity
Plant-Biotic Interactions


 TOP 10 | Microbiology | calculated on 1 December 2008
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1
Exceptional
F1000 Factor 9.8

Hypothesis
New Finding
Novel Drug Target
 Ubiquitin-Like Protein Involved in the Proteasome Pathway of Mycobacterium tuberculosis.
Pearce MJ, Mintseris J, …, Gygi SP, Darwin KH
Science 2008 Oct 2 [abstract on PubMed] [related articles] [full text]
Selected by | Virginia Miller / Tom Rapoport with Ann Marie Stanley / Zhen-Qiang Pan with Antonio Sarikas
First evaluation 16 Oct 2008 | Latest evaluation 6 Nov 2008
 
2
Must Read
F1000 Factor 6.6

Hypothesis
New Finding
 A unique cell division machinery in the Archaea.
Lindås AC, Karlsson EA, …, Ettema TJ, Bernander R
Proc Natl Acad Sci U S A 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | William Margolin / Linda Amos / Harold Erickson / Mohan Balasubramanian with Ramanujam Srinivasan and Mithilesh Mishra
First evaluation 13 Nov 2008 | Latest evaluation 26 Nov 2008
 
3
Must Read
F1000 Factor 6.5

Hypothesis
New Finding
Controversial
 Memory CD8 T-cell compartment grows in size with immunological experience.
Vezys V, Yates A, …, Antia R, Masopust D
Nature 2008 Nov 12 [abstract on PubMed] [related articles] [full text]
Selected by | Barry Rouse / Michael McChesney / David Woodland
First evaluation 18 Nov 2008 | Latest evaluation 26 Nov 2008
 
4
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
 Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.
Mandl JN, Barry AP, …, Staprans SI, Feinberg MB
Nat Med 2008 Oct 14(10):1077-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Grant McFadden / Xiaojing Ma
First evaluation 16 Oct 2008 | Latest evaluation 29 Oct 2008

 
5
Must Read
F1000 Factor 4.8

Confirmation
New Finding
 From the Cover: Horizontal gene transfer of the algal nuclear gene psbO to the photosynthetic sea slug Elysia chlorotica.
Rumpho ME, Worful JM, …, Moustafa A, Manhart JR
Proc Natl Acad Sci U S A 2008 Nov 18 105(46):17867-17871 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Zera / C. Graham Clark
Evaluated 28 Nov 2008
 
6
Must Read
F1000 Factor 4.8

New Finding
Tech Advance
 Extreme substrate promiscuity of the Neisseria oligosaccharyltransferase involved in protein O-glycosylation.
Faridmoayer A, Fentabil MA, …, Wang PG, Feldman MF
J Biol Chem 2008 Oct 17 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miguel Valvano / Barbara Imperiali
First evaluation 30 Oct 2008 | Latest evaluation 19 Nov 2008
 
7
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
Tech Advance
 A stochastic single-molecule event triggers phenotype switching of a bacterial cell.
Choi PJ, Cai L, Frieda K, Xie XS
Science 2008 Oct 17 322(5900):442-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Moir with Andrew Schofield / Jim Maher
First evaluation 29 Oct 2008 | Latest evaluation 5 Nov 2008
 
8
Recommended
F1000 Factor 3.2

New Finding
Tech Advance
Novel Drug Target
 Engineering microRNA responsiveness to decrease virus pathogenicity.
Kelly EJ, Hadac EM, Greiner S, Russell SJ
Nat Med 2008 Nov 14(11):1278-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Crowe / Lynne Maquat with Olaf Isken
First evaluation 12 Nov 2008 | Latest evaluation 19 Nov 2008
 
9
Recommended
F1000 Factor 3.2

Hypothesis
New Finding
Novel Drug Target
 Bacterial protection of beetle-fungus mutualism.
Scott JJ, Oh DC, …, Clardy J, Currie CR
Science 2008 Oct 3 322(5898):63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Keith Chater / Joe Heitman with Yen-Ping Hsueh
Evaluated 24 Oct 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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