Faculty of 1000 Biology | Current Top 10

1-Dec-2008

Top 10s

Developmental Biology

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Developmental Evolution

Developmental Molecular Mechanisms

Morphogenesis & Cell Biology

Pattern Formation

Stem Cells & Regeneration

Related Sections

Leukocyte Development

Microbial Growth & Development

Neurodevelopment

Plant Growth & Development

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	Exceptional
F1000 Factor 10.4

Hypothesis

New Finding

Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Julin Maloof with Jose M. Jimenez-Gomez / Lin Chen with Reza Kalhor / Tom Misteli with Evi Soutoglou

First evaluation 13 Oct 2008 | Latest evaluation 24 Nov 2008

	Exceptional
F1000 Factor 8.2

Hypothesis

New Finding

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.
Wirtz-Peitz F, Nishimura T, Knoblich JA
Cell 2008 Oct 3 135(1):161-73 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Cheng-Yu Lee / Yukiko Yamashita / Valeri Vasioukhin
First evaluation 27 Oct 2008 | Latest evaluation 7 Nov 2008

	Must Read
F1000 Factor 6.6

New Finding

Tech Advance

Single-copy insertion of transgenes in Caenorhabditis elegans.
Frøkjaer-Jensen C, Davis MW, …, Grunnet M, Jorgensen EM
Nat Genet 2008 Nov 40(11):1375-83 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Michel Labouesse / Andy Golden / Susan Mango / Bob Goldstein with Erin McCarthy
First evaluation 5 Nov 2008 | Latest evaluation 19 Nov 2008

	Must Read
F1000 Factor 6.4

New Finding

Tech Advance

Alternative isoform regulation in human tissue transcriptomes.
Wang ET, Sandberg R, …, Schroth GP, Burge CB
Nature 2008 Nov 2 456(7221):470-476 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Ken Irvine with Yongqiang Feng / Donald Rio

First evaluation 20 Nov 2008 | Latest evaluation 1 Dec 2008

	Must Read
F1000 Factor 6.4

New Finding

Tech Advance

Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy.
Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH
Science 2008 Nov 14 322(5904):1065-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Kimelman / Kees Jalink

First evaluation 23 Oct 2008 | Latest evaluation 27 Nov 2008

	Must Read
F1000 Factor 4.8

Hypothesis

New Finding

A model for transmission of the H3K27me3 epigenetic mark.
Hansen KH, Bracken AP, …, Lerdrup M, Helin K
Nat Cell Biol 2008 Nov 10:1291-300 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Leonie Ringrose / Andrew Feinberg

First evaluation 6 Nov 2008 | Latest evaluation 25 Nov 2008

	Must Read
F1000 Factor 4.8

Confirmation

New Finding

Codependent activators direct myoblast-specific MyoD transcription.
Hu P, Geles KG, …, DePinho RA, Tjian R
Dev Cell 2008 Oct 15(4):534-46 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Sassoon with Keren Bismuth / Denis Guttridge
First evaluation 27 Oct 2008 | Latest evaluation 17 Nov 2008

	Recommended
F1000 Factor 3.2

New Finding

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs.
Sun Y, Dykes IM, …, Evans SM, Turner EE
Nat Neurosci 2008 Nov 11(11):1283-93 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Clare Baker / Jane Johnson
First evaluation 5 Nov 2008 | Latest evaluation 6 Nov 2008

	Recommended
F1000 Factor 3.2

Hypothesis

New Finding

MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation.
Tenlen JR, Molk JN, …, Page BD, Priess JR
Development 2008 Oct 8 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Susan Mango / Helen Chamberlin
First evaluation 24 Oct 2008 | Latest evaluation 27 Oct 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.