Faculty of 1000 Biology | Current Top 10

Top 10s

Bioinformatics

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Animal Genetics

Bioinformatics

Biomacromolecule-Ligand Interactions

Cell Signalling & Trafficking Structures

Evolutionary/Comparative Genetics

Experimental Biophysical Methods

Genomics

Macromolecular Assemblies & Machines

Medical Genetics

Membrane Proteins & Energy Transduction

Microbial Evolution & Genomics

Plant Genomes & Evolution

Protein Folding

Structural Genomics

Structure: RNA

Structure: Replication & Repair

Structure: Transcription & Translation

Theory & Simulation

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	Exceptional
F1000 Factor 10.4

Hypothesis

New Finding

Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Julin Maloof with Jose M. Jimenez-Gomez / Lin Chen with Reza Kalhor / Tom Misteli with Evi Soutoglou

First evaluation 13 Oct 2008 | Latest evaluation 24 Nov 2008

	Exceptional
F1000 Factor 10.1

Hypothesis

New Finding

Tech Advance

Structure of a complex of the ATPase SecA and the protein-translocation channel.
Zimmer J, Nam Y, Rapoport TA
Nature 2008 Oct 16 455(7215):936-43 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Manfred Schliwa / Ian Collinson / Art Horwich / Martin Pool

First evaluation 31 Oct 2008 | Latest evaluation 28 Nov 2008

	Must Read
F1000 Factor 4.8

Hypothesis

New Finding

Tech Advance

Controversial

Remeasuring the double helix.
Mathew-Fenn RS, Das R, Harbury PA
Science 2008 Oct 17 322(5900):446-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | P. Shing Ho / Jim Maher
First evaluation 28 Oct 2008 | Latest evaluation 5 Nov 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.