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Do ligand binding and solvent exclusion alter the electrostatic character within the oxyanion hole of an enzymatic active site?

Sigala PA, Fafarman AT, Bogard PE, Boxer SG, Herschlag D.

Departments of Chemistry and Biochemistry, Stanford University, Stanford, California 94305-5307, USA.

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PMID: 17854190 [PubMed - indexed for MEDLINE]