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Exceptional
F1000 Factor
9.0
Hypothesis
New Finding
Novel Drug Target
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway.
Park KK, Liu K, …, Sahin M, He Z
Science
2008 Nov 7
322
(5903):963-6 [
abstract on PubMed
] [
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full text
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Selected by
| Vance Lemmon with Jessica K Lerch-Haner
Evaluated 28 Nov 2008
Recommended
F1000 Factor
3.0
Hypothesis
New Finding
A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.
Li X, Ito M, …, Leder P, Ferguson-Smith AC
Dev Cell
2008 Oct
15
(4):547-57 [
abstract on PubMed
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full text
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Selected by
| Wolf Reik
Evaluated 25 Nov 2008
Recommended
F1000 Factor
3.2
Hypothesis
New Finding
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.
Tay Y, Zhang J, …, Lim B, Rigoutsos I
Nature
2008 Oct 23
455
(7216):1124-8 [
abstract on PubMed
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Selected by
| Yi Eve Sun with Weihong Ge
/ Peter Sarnow with Cara Pager
First evaluation 25 Nov 2008 | Latest evaluation 27 Nov 2008
Must Read
F1000 Factor
6.0
New Finding
Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity.
Ullah Z, Kohn MJ, …, Vassilev LT, Depamphilis ML
Genes Dev
2008 Nov 1
22
(21):3024-36 [
abstract on PubMed
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Selected by
| Marcel Mechali
Evaluated 21 Nov 2008
Recommended
F1000 Factor
3.0
New Finding
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation.
Luis TC, Weerkamp F, …, van Dongen JJ, Staal FJ
Blood
2008 Oct 2 [
abstract on PubMed
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full text
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Selected by
| Hans-Willem Snoeck
Evaluated 21 Nov 2008
Must Read
F1000 Factor
4.8
New Finding
Novel Drug Target
Rac activation and inactivation control plasticity of tumor cell movement.
Sanz-Moreno V, Gadea G, …, Sahai E, Marshall CJ
Cell
2008 Oct 31
135
(3):510-23 [
abstract on PubMed
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Selected by
| Richard Klemke / Martin A. Schwartz
First evaluation 13 Nov 2008 | Latest evaluation 24 Nov 2008
Recommended
F1000 Factor
3.0
New Finding
Tech Advance
Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin.
Kanatsu-Shinohara M, Takehashi M, …, Fässler R, Shinohara T
Cell Stem Cell
2008 Nov 6
3
(5):533-42 [
abstract on PubMed
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full text
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Selected by
| Erika Matunis
Evaluated 13 Nov 2008
Exceptional
F1000 Factor
9.0
Hypothesis
New Finding
Tech Advance
Global reorganization of replication domains during embryonic stem cell differentiation.
Hiratani I, Ryba T, …, Schübeler D, Gilbert DM
PLoS Biol
2008 Oct 7
6
(10):e245 [
abstract on PubMed
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FREE full text
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Selected by
| Joel Huberman
Evaluated 11 Nov 2008
Recommended
F1000 Factor
3.0
Hypothesis
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation.
Duncan EM, Muratore-Schroeder TL, …, Hunt DF, Allis CD
Cell
2008 Oct 17
135
(2):284-94 [
abstract on PubMed
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Selected by
| Michael Cole with Seth J. Brown
Evaluated 7 Nov 2008
Must Read
F1000 Factor
6.0
New Finding
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.
Mohn F, Weber M, …, Bibel M, Schübeler D
Mol Cell
2008 Jun 20
30
(6):755-66 [
abstract on PubMed
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Selected by
| Magdalena Götz
Evaluated 29 Oct 2008
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