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Browse > Pharmacology & Drug Discovery > Cardiovascular Pharmacology
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F1000 Factor 3.0

New Finding
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 The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.
Sapieha P, Sirinyan M, …, Sennlaub F, Chemtob S
Nat Med 2008 Oct 14(10):1067-76 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Raymond Harris
Evaluated 17 Nov 2008

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 Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure.
Watanabe T, Takeda T, …, Shirasawa T, Otsu K
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Selected by | Michael Frenneaux with Julian O M Ormerod
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F1000 Factor 6.0

Hypothesis
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 Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.
Chen CH, Budas GR, …, Hurley TD, Mochly-Rosen D
Science 2008 Sep 12 321(5895):1493-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Triggle
Evaluated 11 Nov 2008

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F1000 Factor 6.0

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 Sox18 induces development of the lymphatic vasculature in mice.
François M, Caprini A, …, Dejana E, Koopman P
Nature 2008 Oct 19 [abstract on PubMed] [related articles] [full text]
Selected by | Friedemann Kiefer
Evaluated 5 Nov 2008

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F1000 Factor 6.0

New Finding
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 Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome.
Sale H, Wang J, …, Ackerman MJ, Robertson GA
Circ Res 2008 Sep 26 103(7):e81-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stanley Nattel
Evaluated 5 Nov 2008

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 ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
Noma K, Rikitake Y, …, Sun J, Liao JK
J Clin Invest 2008 May 118(5):1632-44 [abstract on PubMed] [related articles] [FREE full text]
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 Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention.
Ge Y, Bagnall AJ, …, Kotelevtsev YV, Kohan DE
Am J Physiol Renal Physiol 2008 Sep 10 [abstract on PubMed] [related articles] [full text]
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 Doxorubicin induces early lipid peroxidation associated with changes in glucose transport in cultured cardiomyocytes.
Hrelia S, Fiorentini D, …, Biagi PL, Hakim G
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Selected by | Michael Reid with Melissa Chambers
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 Glucocorticoid Receptor Gene Variant in the 3' Untranslated Region is Associated with Multiple Measures of Blood Pressure.
Chung CC, Shimmin L, …, Boerwinkle E, Hixson JE
J Clin Endocrinol Metab 2008 Oct 14 [abstract on PubMed] [related articles] [full text]
Selected by | Julia Buckingham
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 Genetic polymorphisms of NAD(P)H oxidase: variation in subunit expression and enzyme activity.
Schirmer M, Hoffmann M, …, Tzvetkov M, Brockmöller J
Pharmacogenomics J 2008 Aug 8(4):297-304 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ines Armando
Evaluated 23 Oct 2008


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