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Browse > Pharmacology & Drug Discovery > Immunopharmacology & Hematologic Pharmacology
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F1000 Factor 3.0

Hypothesis
New Finding
 Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF.
Yago T, Lou J, …, McEver RP, Zhu C
J Clin Invest 2008 Sep 118(9):3195-207 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Xiaoping Du
Evaluated 20 Nov 2008

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F1000 Factor 3.0

New Finding
 Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I IFN, and immune suppression.
Malleret B, Maneglier B, …, Le Grand R, Vaslin B
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Selected by | Gene Shearer with Adriano Boasso
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F1000 Factor 6.0

New Finding
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Vezys V, Yates A, …, Antia R, Masopust D
Nature 2008 Nov 12 [abstract on PubMed] [related articles] [full text]
Selected by | Barry Rouse
Evaluated 18 Nov 2008

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F1000 Factor 3.0

Confirmation
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Schneider A, Rieck M, …, Greenbaum C, Buckner JH
J Immunol 2008 Nov 15 181(10):7350-5 [abstract on PubMed] [related articles] [order article]
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Evaluated 14 Nov 2008

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F1000 Factor 3.0

New Finding
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 Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation.
Jackson NE, Wang HW, …, Cairns J, Hunt JE
J Biol Chem 2008 Oct 14 [abstract on PubMed] [related articles] [FREE full text]
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Evaluated 13 Nov 2008

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F1000 Factor 3.2

New Finding
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Kelly EJ, Hadac EM, Greiner S, Russell SJ
Nat Med 2008 Nov 14(11):1278-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Crowe / Lynne Maquat with Olaf Isken
First evaluation 12 Nov 2008 | Latest evaluation 19 Nov 2008

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F1000 Factor 6.0

New Finding
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 Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.
Rubic T, Lametschwandtner G, …, Rot A, Carballido JM
Nat Immunol 2008 Nov 9(11):1261-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mauro Teixeira
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F1000 Factor 3.0

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 Activation of a dendritic cell-T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells.
Perreau M, Pantaleo G, Kremer EJ
J Exp Med 2008 Nov 3 [abstract on PubMed] [related articles] [full text]
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F1000 Factor 3.0

New Finding
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 ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
Noma K, Rikitake Y, …, Sun J, Liao JK
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Selected by | Ivan McMurtry
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F1000 Factor 6.0

New Finding
 TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice.
McKinley L, Alcorn JF, …, Ray A, Kolls JK
J Immunol 2008 Sep 15 181(6):4089-97 [abstract on PubMed] [related articles] [order article]
Selected by | Dan Conrad
Evaluated 31 Oct 2008


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