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Renal, Fluid & Electrolyte Physiology
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Must Read
F1000 Factor 6.0

Confirmation
Identification of alpha(1L)-adrenoceptor in mice and its abolition by alpha(1A)-adrenoceptor gene knockout.
Muramatsu I, Morishima S, …, Myagmar BE, Simpson PC
Br J Pharmacol 2008 Sep 22 [abstract on PubMed] [related articles] [full text]
Selected by | Rodolfo Testa with Patrizia Angelico
Evaluated 1 Dec 2008

Recommended
F1000 Factor 3.0

Confirmation
Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone.
Pochynyuk O, Bugaj V, …, Vallon V, Stockand JD
J Biol Chem 2008 Nov 3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 17 Nov 2008

Must Read
F1000 Factor 6.0

Tech Advance
Rapid determination of renal filtration function using an optical ratiometric imaging approach.
Yu W, Sandoval RM, Molitoris BA
Am J Physiol Renal Physiol 2007 Jun 292(6):F1873-80 [abstract on PubMed] [related articles] [FREE full text]
Selected by | José Carlos Peña
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Rescue of volume-regulated anion current by bestrophin mutants with altered charge selectivity.
Chien LT, Hartzell HC
J Gen Physiol 2008 Nov 132(5):537-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bernd Nilius
Evaluated 10 Nov 2008

Must Read
F1000 Factor 4.8

New Finding
Refutation
The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm.
Weavers H, Prieto-Sánchez S, …, Skaer H, Denholm B
Nature 2008 Oct 29 [abstract on PubMed] [related articles] [full text]
Selected by | David Bates / Matthew Breyer
First evaluation 7 Nov 2008 | Latest evaluation 28 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Novel Drug Target
Netrin-1 and kidney injury. II. Netrin-1 is an early biomarker of acute kidney injury.
Brian Reeves W, Kwon O, Ramesh G
Am J Physiol Renal Physiol 2008 Apr 294(4):F731-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giovambattista Capasso
Evaluated 4 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
Controversial
Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention.
Ge Y, Bagnall AJ, …, Kotelevtsev YV, Kohan DE
Am J Physiol Renal Physiol 2008 Sep 10 [abstract on PubMed] [related articles] [full text]
Selected by | David Pollock
Evaluated 31 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Programming Neuroendocrine Stress Axis Activity by Exposure to Glucocorticoids during Postembryonic Development of the Frog, Xenopus laevis.
Hu F, Crespi EJ, Denver RJ
Endocrinology 2008 Nov 149(11):5470-81 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Megan Holmes with Caitlin Wyrwoll
Evaluated 31 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL.
Chitalia VC, Foy RL, …, Dominguez I, Cohen HT
Nat Cell Biol 2008 Oct 10(10):1208-16 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Chernoff
Evaluated 30 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
Rapid nongenomic effects of aldosterone on the renal vasculature in humans.
Schmidt BM, Sammer U, …, Delles C, Schmieder RE
Hypertension 2006 Apr 47(4):650-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 29 Oct 2008


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