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Must Read
F1000 Factor 6.0

New Finding
Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin.
Hennies HC, Kornak U, …, Wieacker P, Mundlos S
Nat Genet 2008 Nov 9 [abstract on PubMed] [related articles] [full text]
Selected by | Peter McPherson
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
Purinergic receptors and synaptic transmission in enteric neurons.
Ren J, Bertrand PP
Purinergic Signal 2008 Sep 4(3):255-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Geoffrey Burnstock
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.6

Hypothesis
New Finding
HARP is an ATP-driven annealing helicase.
Yusufzai T, Kadonaga JT
Science 2008 Oct 31 322(5902):748-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Botchan / Lucio Comai / Jessica Downs
First evaluation 13 Nov 2008 | Latest evaluation 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Self-renewal and expansion of single transplanted muscle stem cells.
Sacco A, Doyonnas R, …, Vitorovic S, Blau HM
Nature 2008 Sep 17 [abstract on PubMed] [related articles] [full text]
Selected by | Carlo Reggiani with Marco Quarta
Evaluated 11 Nov 2008


Must Read
F1000 Factor 6.0

New Finding
Tech Advance
Lgr5 marks cycling, yet long-lived, hair follicle stem cells.
Jaks V, Barker N, …, Clevers H, Toftgård R
Nat Genet 2008 Oct 12 [abstract on PubMed] [related articles] [full text]
Selected by | Bruce Morgan
Evaluated 28 Oct 2008

Must Read
F1000 Factor 4.8

Confirmation
New Finding
Codependent activators direct myoblast-specific MyoD transcription.
Hu P, Geles KG, …, DePinho RA, Tjian R
Dev Cell 2008 Oct 15(4):534-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Sassoon with Keren Bismuth / Denis Guttridge
First evaluation 27 Oct 2008 | Latest evaluation 17 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance.
Nara N, Nakayama Y, …, Minokoshi Y, Hara T
J Biol Chem 2007 Oct 19 282(42):30794-803 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Amira Klip with Jonathan Schertzer
Evaluated 24 Oct 2008

Must Read
F1000 Factor 6.4

New Finding
Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK.
Kim N, Stiegler AL, …, Dustin ML, Burden SJ
Cell 2008 Oct 8 [abstract on PubMed] [related articles] [full text]
Selected by | Markus Ruegg / David Ginty
First evaluation 24 Oct 2008 | Latest evaluation 31 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Association between 5-alpha reductase inhibition and risk of hip fracture.
Jacobsen SJ, Cheetham TC, …, Shi JM, Loo RK
JAMA 2008 Oct 8 300(14):1660-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Amory
Evaluated 24 Oct 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Loss of protein kinase C{epsilon} results in impaired cutaneous wound closure and myofibroblast function.
Leask A, Shi-Wen X, …, Black CM, Abraham DJ
J Cell Sci 2008 Oct 15 121(Pt 20):3459-67 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Giulio Gabbiani
Evaluated 23 Oct 2008


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