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Recommended
F1000 Factor 3.0

Hypothesis
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice.
Troy S, Soty M, …, Mithieux G, Andreelli F
Cell Metab 2008 Sep 8(3):201-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joel Elmquist with Kevin W. Williams
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Environmental novelty is signaled by reduction of the hippocampal theta frequency.
Jeewajee A, Lever C, …, O'Keefe J, Burgess N
Hippocampus 2008 18(4):340-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Edvard I. Moser with Dori Derdikman
Evaluated 17 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
Novel Drug Target
Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal.
Surget A, Saxe M, …, Hen R, Belzung C
Biol Psychiatry 2008 Aug 15 64(4):293-301 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Esther Sternberg with Marni Silverman
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Neural circuitry of stress-induced insomnia in rats.
Cano G, Mochizuki T, Saper CB
J Neurosci 2008 Oct 1 28(40):10167-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Luis de Lecea
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory.
Lubin FD, Roth TL, Sweatt JD
J Neurosci 2008 Oct 15 28(42):10576-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Manfred Gahr
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
Purinergic receptors and synaptic transmission in enteric neurons.
Ren J, Bertrand PP
Purinergic Signal 2008 Sep 4(3):255-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Geoffrey Burnstock
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Controversial
Novel Drug Target
Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression.
Ghia JE, Blennerhassett P, Collins SM
J Clin Invest 2008 Jun 118(6):2209-18 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ruud Buijs
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Phase resetting of the mammalian circadian clock by DNA damage.
Oklejewicz M, Destici E, …, Janssens R, van der Horst GT
Curr Biol 2008 Feb 26 18(4):286-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean Clairambault
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity.
Aoto J, Nam CI, …, Ting P, Chen L
Neuron 2008 Oct 23 60(2):308-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Johannes Hell
Evaluated 11 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Conditioning of stimuli with nonzero initial value.
Rescorla RA
J Exp Psychol Anim Behav Process 2008 Jul 34(3):315-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Terry Davidson
Evaluated 11 Nov 2008


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