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Browse > Physiology > Integrative Physiology
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F1000 Factor 3.0

Tech Advance
 The transition from differential equations to Boolean networks: a case study in simplifying a regulatory network model.
Davidich M, Bornholdt S
J Theor Biol 2008 Dec 7 255(3):269-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Maini
Evaluated 19 Nov 2008

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F1000 Factor 6.0

Hypothesis
New Finding
 Glucose induces an autocrine activation of the Wnt/beta-catenin pathway in macrophage cell lines.
Anagnostou SH, Shepherd PR
Biochem J 2008 Dec 1 416(2):211-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alex Toker
Evaluated 18 Nov 2008

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 Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice.
Troy S, Soty M, …, Mithieux G, Andreelli F
Cell Metab 2008 Sep 8(3):201-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joel Elmquist with Kevin W. Williams
Evaluated 18 Nov 2008

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F1000 Factor 3.0

New Finding
Novel Drug Target
 The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.
Sapieha P, Sirinyan M, …, Sennlaub F, Chemtob S
Nat Med 2008 Oct 14(10):1067-76 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Raymond Harris
Evaluated 17 Nov 2008

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F1000 Factor 3.0

Hypothesis
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 Neural circuitry of stress-induced insomnia in rats.
Cano G, Mochizuki T, Saper CB
J Neurosci 2008 Oct 1 28(40):10167-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Luis de Lecea
Evaluated 17 Nov 2008

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F1000 Factor 6.0

New Finding
 Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.
Suzuki T, Sakagami T, …, van der Loo JC, Trapnell BC
J Exp Med 2008 Oct 27 [abstract on PubMed] [related articles] [full text]
Selected by | Glenn Dranoff
Evaluated 17 Nov 2008

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New Finding
 PirB is a functional receptor for myelin inhibitors of axonal regeneration.
Atwal JK, Pinkston-Gosse J, …, Shatz C, Tessier-Lavigne M
Science 2008 Nov 7 322(5903):967-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Susan K. McConnell
Evaluated 14 Nov 2008

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 Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory.
Lubin FD, Roth TL, Sweatt JD
J Neurosci 2008 Oct 15 28(42):10576-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Manfred Gahr
Evaluated 14 Nov 2008

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Confirmation
 Purinergic receptors and synaptic transmission in enteric neurons.
Ren J, Bertrand PP
Purinergic Signal 2008 Sep 4(3):255-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Geoffrey Burnstock
Evaluated 14 Nov 2008

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F1000 Factor 6.0

Tech Advance
 Rapid determination of renal filtration function using an optical ratiometric imaging approach.
Yu W, Sandoval RM, Molitoris BA
Am J Physiol Renal Physiol 2007 Jun 292(6):F1873-80 [abstract on PubMed] [related articles] [FREE full text]
Selected by | José Carlos Peña
Evaluated 14 Nov 2008


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