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Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
Controversial
The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.
Nilsson J, Yekezare M, Minshull J, Pines J
Nat Cell Biol 2008 Nov 9 [abstract on PubMed] [related articles] [full text]
Selected by | Kevin Hardwick
Evaluated 20 Nov 2008

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
Homologous recombination in real time: DNA strand exchange by RecA.
van der Heijden T, Modesti M, …, Wyman C, Dekker C
Mol Cell 2008 May 23 30(4):530-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Johannes Walter
Evaluated 20 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Actin dynamics is essential for myosin-based transport of membrane organelles.
Semenova I, Burakov A, …, Kashina A, Rodionov V
Curr Biol 2008 Oct 28 18(20):1581-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Akhmanova
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs.
Hirota K, Miyoshi T, …, Shibata T, Ohta K
Nature 2008 Nov 6 456(7218):130-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniel Reines
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
A Role for the ESCRT System in Cell Division in Archaea.
Samson RY, Obita T, …, Williams RL, Bell SD
Science 2008 Nov 13 [abstract on PubMed] [related articles] [full text]
Selected by | Linda Amos
Evaluated 17 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome.
Zhao J, Sun BK, …, Song JJ, Lee JT
Science 2008 Oct 31 322(5902):750-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brad Bernstein
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Sentan: A Novel Specific Component of the Apical Structure of Vertebrate Motile Cilia.
Kubo A, Yuba-Kubo A, …, Tsukita S, Amagai M
Mol Biol Cell 2008 Oct 1 [abstract on PubMed] [related articles] [FREE full text]
Selected by | George Witman
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery.
Ahmed NT, Gao C, …, Cole DG, Mitchell DR
J Cell Biol 2008 Oct 20 183(2):313-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | George Witman
Evaluated 13 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus.
Bornholdt ZA, Prasad BV
Nature 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | Samuel Butcher
Evaluated 13 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Splicing factors facilitate RNAi-directed silencing in fission yeast.
Bayne EH, Portoso M, …, Rappsilber J, Allshire RC
Science 2008 Oct 24 322(5901):602-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Craig Pikaard
Evaluated 13 Nov 2008


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