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F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
Kvansakul M, Yang H, …, Huang DC, Colman PM
Cell Death Differ 2008 Oct 15(10):1564-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Andrews
Evaluated 18 Nov 2008

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F1000 Factor 6.0

New Finding
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus.
Bornholdt ZA, Prasad BV
Nature 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | Samuel Butcher
Evaluated 13 Nov 2008

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F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
Crystal Structure of a Ten-Amino Acid Protein.
Honda S, Akiba T, …, Odahara T, Harata K
J Am Chem Soc 2008 Oct 25 0 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Torleif Härd
Evaluated 12 Nov 2008

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F1000 Factor 4.8

New Finding
Tech Advance
Global protein stability profiling in mammalian cells.
Yen HC, Xu Q, …, Zhao Z, Elledge SJ
Science 2008 Nov 7 322(5903):918-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Berl R. Oakley / Hunter Fraser
First evaluation 12 Nov 2008 | Latest evaluation 18 Nov 2008

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F1000 Factor 3.0

New Finding
Tech Advance
Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization.
Kerff F, Amoroso A, …, Nikolaidis N, Cosgrove DJ
Proc Natl Acad Sci U S A 2008 Oct 29 [abstract on PubMed] [related articles] [full text]
Selected by | Jocelyn Rose
Evaluated 6 Nov 2008

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F1000 Factor 3.0

Confirmation
A quantitative model of thermal stabilization and destabilization of proteins by ligands.
Cimmperman P, Baranauskiene L, …, Bumelis V, Matulis D
Biophys J 2008 Oct 95(7):3222-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Schuck with Huaying Zhao
Evaluated 29 Oct 2008

Exceptional
F1000 Factor 9.0

Tech Advance
Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules.
Hodis E, Prilusky J, …, Moult J, Sussman JL
Genome Biol 2008 Aug 3 9(8):R121 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Burkhard Rost
Evaluated 29 Oct 2008

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F1000 Factor 3.0

Tech Advance
The complete VS ribozyme in solution studied by small-angle X-ray scattering.
Lipfert J, Ouellet J, …, Doniach S, Lilley DM
Structure 2008 Sep 10 16(9):1357-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tamar Schlick with Christian Laing
Evaluated 28 Oct 2008

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F1000 Factor 6.0

Hypothesis
New Finding
Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin.
Surolia I, Sinha S, …, Reddy GB, Surolia A
PLoS ONE 2008 3(8):e2927 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Narayanaswamy Srinivasan
Evaluated 24 Oct 2008

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F1000 Factor 3.0

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Algorithm for backrub motions in protein design.
Georgiev I, Keedy D, …, Richardson DC, Donald BR
Bioinformatics 2008 Jul 1 24(13):i196-204 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Narayanaswamy Srinivasan
Evaluated 24 Oct 2008


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