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Browse > Structural Biology > Structure: RNA
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Must Read
F1000 Factor 6.0

New Finding
 X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus.
Bornholdt ZA, Prasad BV
Nature 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | Samuel Butcher
Evaluated 13 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Splicing factors facilitate RNAi-directed silencing in fission yeast.
Bayne EH, Portoso M, …, Rappsilber J, Allshire RC
Science 2008 Oct 24 322(5901):602-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Craig Pikaard
Evaluated 13 Nov 2008

Must Read
F1000 Factor 6.6

Hypothesis
New Finding
 HARP is an ATP-driven annealing helicase.
Yusufzai T, Kadonaga JT
Science 2008 Oct 31 322(5902):748-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Botchan / Lucio Comai / Jessica Downs
First evaluation 13 Nov 2008 | Latest evaluation 17 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Toward predicting self-splicing and protein-facilitated splicing of group I introns.
Vicens Q, Paukstelis PJ, …, Lambowitz AM, Cech TR
RNA 2008 Oct 14(10):2013-29 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Niles Lehman with Aaron S. Burton
Evaluated 30 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26.
Ofir-Rosenfeld Y, Boggs K, …, Kastan MB, Oren M
Mol Cell 2008 Oct 24 32(2):180-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan R. Warner
Evaluated 30 Oct 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
 Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Chi YI, Martick M, …, Scott WG, Kim SH
PLoS Biol 2008 Sep 30 6(9):e234 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Pascale Legault
Evaluated 30 Oct 2008

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Structure and function of an RNase H domain at the heart of the spliceosome.
Pena V, Rozov A, …, Lührmann R, Wahl MC
EMBO J 2008 Oct 9 [abstract on PubMed] [related articles] [full text]
Selected by | Eric Westhof
Evaluated 30 Oct 2008

Recommended
F1000 Factor 3.0

Tech Advance
 The complete VS ribozyme in solution studied by small-angle X-ray scattering.
Lipfert J, Ouellet J, …, Doniach S, Lilley DM
Structure 2008 Sep 10 16(9):1357-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tamar Schlick with Christian Laing
Evaluated 28 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 G-Quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC.
Gros J, Guédin A, Mergny JL, Lacroix L
Chembiochem 2008 Sep 1 9(13):2075-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama with Yan Xu
Evaluated 20 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Primary microRNA transcripts are processed co-transcriptionally.
Morlando M, Ballarino M, …, Bozzoni I, Proudfoot NJ
Nat Struct Mol Biol 2008 Aug 31 [abstract on PubMed] [related articles] [full text]
Selected by | Kevin J. Luebke
Evaluated 17 Oct 2008


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