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Must Read
F1000 Factor 6.0

Tech Advance
Real-Time DNA Sequencing from Single Polymerase Molecules.
Eid J, Fehr A, …, Korlach J, Turner S
Science 2008 Nov 20 [abstract on PubMed] [related articles] [full text]
Selected by | Michal Lebl
Evaluated 1 Dec 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
Unnatural substrate repertoire of A, B, and X family DNA polymerases.
Hwang GT, Romesberg FE
J Am Chem Soc 2008 Nov 5 130(44):14872-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Kuchta
Evaluated 28 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates.
Paeschke K, Juranek S, …, Rhodes D, Lipps HJ
Nat Struct Mol Biol 2008 Jun 15(6):598-604 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama with Yan Xu
Evaluated 27 Nov 2008

Must Read
F1000 Factor 6.0

Tech Advance
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases.
Redondo P, Prieto J, …, Blanco FJ, Montoya G
Nature 2008 Nov 6 456(7218):107-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ulf Pettersson
Evaluated 21 Nov 2008

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
Homologous recombination in real time: DNA strand exchange by RecA.
van der Heijden T, Modesti M, …, Wyman C, Dekker C
Mol Cell 2008 May 23 30(4):530-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Johannes Walter
Evaluated 20 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Phase resetting of the mammalian circadian clock by DNA damage.
Oklejewicz M, Destici E, …, Janssens R, van der Horst GT
Curr Biol 2008 Feb 26 18(4):286-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean Clairambault
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Human DNA polymerase iota protects cells against oxidative stress.
Petta TB, Nakajima S, …, Yasui A, Kannouche P
EMBO J 2008 Nov 5 27(21):2883-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Lehmann
Evaluated 13 Nov 2008

Must Read
F1000 Factor 6.6

Hypothesis
New Finding
HARP is an ATP-driven annealing helicase.
Yusufzai T, Kadonaga JT
Science 2008 Oct 31 322(5902):748-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Botchan / Lucio Comai / Jessica Downs
First evaluation 13 Nov 2008 | Latest evaluation 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase.
Nagai S, Dubrana K, …, Gasser SM, Krogan NJ
Science 2008 Oct 24 322(5901):597-602 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Brill
Evaluated 12 Nov 2008

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Tech Advance
Global reorganization of replication domains during embryonic stem cell differentiation.
Hiratani I, Ryba T, …, Schübeler D, Gilbert DM
PLoS Biol 2008 Oct 7 6(10):e245 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joel Huberman
Evaluated 11 Nov 2008


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