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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Controversial
 Hierarchical coding for sequential task events in the monkey prefrontal cortex.
Sigala N, Kusunoki M, …, Gaffan D, Duncan J
Proc Natl Acad Sci U S A 2008 Aug 19 105(33):11969-74 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Susan Courtney
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 A small molecule enhances RNA interference and promotes microRNA processing.
Shan G, Li Y, …, He C, Jin P
Nat Biotechnol 2008 Aug 26(8):933-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gabriele Varani
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
Du H, Guo L, …, Chen JX, Yan SD
Nat Med 2008 Oct 14(10):1097-105 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Heinz Osiewacz
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 PirB is a functional receptor for myelin inhibitors of axonal regeneration.
Atwal JK, Pinkston-Gosse J, …, Shatz C, Tessier-Lavigne M
Science 2008 Nov 7 322(5903):967-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Susan K. McConnell
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 Persistently active, pacemaker-like neurons in neocortex.
Le Bon-Jego M, Yuste R
Front Neurosci 2007 Nov 1(1):123-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alain Destexhe
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory.
Lubin FD, Roth TL, Sweatt JD
J Neurosci 2008 Oct 15 28(42):10576-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Manfred Gahr
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Controversial
 Dendritic NMDA receptors activate axonal calcium channels.
Christie JM, Jahr CE
Neuron 2008 Oct 23 60(2):298-307 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Ehlers
Evaluated 12 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Maintenance of axo-oligodendroglial paranodal junctions requires DCC and netrin-1.
Jarjour AA, Bull SJ, …, Di Polo A, Kennedy TE
J Neurosci 2008 Oct 22 28(43):11003-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Elior Peles
Evaluated 11 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis.
Lonigro A, Devaux JJ
Brain 2008 Oct 25 [abstract on PubMed] [related articles] [full text]
Selected by | Elior Peles
Evaluated 11 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
 On the spontaneous emergence of cell polarity.
Altschuler SJ, Angenent SB, Wang Y, Wu LF
Nature 2008 Aug 14 454(7206):886-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carlos Dotti
Evaluated 11 Nov 2008


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