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Browse > Immunology > Immunity to Infections
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Recommended
F1000 Factor 3.0

Hypothesis
 Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway.
Strong JE, Wong G, …, Kobinger GP, Feldmann H
Proc Natl Acad Sci U S A 2008 Nov 3 105 [abstract on PubMed] [related articles] [full text]
Selected by | Kanta Subbarao with Catherine Luke
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I IFN, and immune suppression.
Malleret B, Maneglier B, …, Le Grand R, Vaslin B
Blood 2008 Sep 11 [abstract on PubMed] [related articles] [full text]
Selected by | Gene Shearer with Adriano Boasso
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 Memory CD8 T-cell compartment grows in size with immunological experience.
Vezys V, Yates A, …, Antia R, Masopust D
Nature 2008 Nov 12 [abstract on PubMed] [related articles] [full text]
Selected by | Barry Rouse
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
 The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster.
Tucker NP, Hicks MG, …, Dixon R, Hutchings MI
PLoS ONE 2008 3(11):e3623 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Spiro
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Controversial
Novel Drug Target
 Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression.
Ghia JE, Blennerhassett P, Collins SM
J Clin Invest 2008 Jun 118(6):2209-18 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ruud Buijs
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus.
Bornholdt ZA, Prasad BV
Nature 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | Samuel Butcher
Evaluated 13 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Novel Drug Target
 Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation.
Jackson NE, Wang HW, …, Cairns J, Hunt JE
J Biol Chem 2008 Oct 14 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard L. Stevens
Evaluated 13 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Substrains of 129 mice are resistant to Yersinia pestis KIM5: Implications for IL-10 deficient mice.
Turner JK, Xu JL, Tapping RI
Infect Immun 2008 Oct 27 [abstract on PubMed] [related articles] [full text]
Selected by | James Bliska
Evaluated 11 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity.
Cella M, Fuchs A, …, Mills JC, Colonna M
Nature 2008 Nov 2 [abstract on PubMed] [related articles] [full text]
Selected by | Mauro Teixeira
Evaluated 10 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Tech Advance
 Dynamics of human respiratory virus-specific CD8+ T cell responses in blood and airways during episodes of common cold.
Heidema J, Rossen JW, …, Kimpen JL, van Bleek GM
J Immunol 2008 Oct 15 181(8):5551-9 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Openshaw
Evaluated 10 Nov 2008


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