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20-Nov-2008

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	Must Read
F1000 Factor 6.0

New Finding

Tech Advance

Molecular Engineering of Photoremovable Protecting Groups for Two-Photon Uncaging.
Gug S, Bolze F, …, Goeldner M, Nicoud JF
Angew Chem Int Ed Engl 2008 Oct 29 [abstract on PubMed] [related articles] [full text]

Selected by | Michael Pirrung

Evaluated 18 Nov 2008

	Recommended
F1000 Factor 3.0

Tech Advance

Novel Drug Target

Generating Arrays with High Content and Minimal Consumption of Functional Membrane Proteins.
Majd S, Mayer M
J Am Chem Soc 2008 Nov 1 0 [abstract on PubMed] [related articles] [full text]

Selected by | Ross Weatherman

Evaluated 17 Nov 2008

	Recommended
F1000 Factor 3.0

New Finding

Tech Advance

Seleninate in place of phosphate: irreversible inhibition of protein tyrosine phosphatases.
Abdo M, Liu S, …, Knapp S, Zhang ZY
J Am Chem Soc 2008 Oct 8 130(40):13196-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Philip Cole

Evaluated 14 Nov 2008

	Must Read
F1000 Factor 6.0

New Finding

X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus.
Bornholdt ZA, Prasad BV
Nature 2008 Nov 5 [abstract on PubMed] [related articles] [full text]

Selected by | Samuel Butcher

Evaluated 13 Nov 2008

	Must Read
F1000 Factor 6.0

New Finding

Tech Advance

Single-particle kinetics of influenza virus membrane fusion.
Floyd DL, Ragains JR, …, Harrison SC, van Oijen AM
Proc Natl Acad Sci U S A 2008 Oct 7 105(40):15382-7 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Lukas Tamm with Volker Kiessling
Evaluated 10 Nov 2008

	Recommended
F1000 Factor 3.0

Confirmation

Controversial

Test of the Gouy-Chapman theory for a charged lipid membrane against explicit-solvent molecular dynamics simulations.
Yi M, Nymeyer H, Zhou HX
Phys Rev Lett 2008 Jul 18 101(3):038103 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Qiang Cui
Evaluated 4 Nov 2008

	Recommended
F1000 Factor 3.0

New Finding

Tech Advance

Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine.
Lee S, Bowman BR, …, Wang S, Verdine GL
J Am Chem Soc 2008 Sep 3 130(35):11570-1 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Stephen Woski
Evaluated 3 Nov 2008

	Recommended
F1000 Factor 3.0

Hypothesis

New Finding

Toward predicting self-splicing and protein-facilitated splicing of group I introns.
Vicens Q, Paukstelis PJ, …, Lambowitz AM, Cech TR
RNA 2008 Oct 14(10):2013-29 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Niles Lehman with Aaron S. Burton
Evaluated 30 Oct 2008

	Must Read
F1000 Factor 4.8

New Finding

Tech Advance

Extreme substrate promiscuity of the Neisseria oligosaccharyltransferase involved in protein O-glycosylation.
Faridmoayer A, Fentabil MA, …, Wang PG, Feldman MF
J Biol Chem 2008 Oct 17 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Miguel Valvano / Barbara Imperiali

First evaluation 30 Oct 2008 | Latest evaluation 19 Nov 2008

	Must Read
F1000 Factor 6.0

Confirmation

Controversial

Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex.
Urano Y, Watanabe H, …, Chang CC, Chang TY
Proc Natl Acad Sci U S A 2008 Oct 22 [abstract on PubMed] [related articles] [full text]

Selected by | Markus Engstler
Evaluated 29 Oct 2008

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