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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Actin dynamics is essential for myosin-based transport of membrane organelles.
Semenova I, Burakov A, …, Kashina A, Rodionov V
Curr Biol 2008 Oct 28 18(20):1581-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Akhmanova
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
 {alpha}- and {beta}- Monosaccharide Transport in Human Erythrocytes.
Carruthers A, Leitch J
Am J Physiol Cell Physiol 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | Richard J Naftalin
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Molecular Engineering of Photoremovable Protecting Groups for Two-Photon Uncaging.
Gug S, Bolze F, …, Goeldner M, Nicoud JF
Angew Chem Int Ed Engl 2008 Oct 29 [abstract on PubMed] [related articles] [full text]
Selected by | Michael Pirrung
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
 The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster.
Tucker NP, Hicks MG, …, Dixon R, Hutchings MI
PLoS ONE 2008 3(11):e3623 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Spiro
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
Tech Advance
Novel Drug Target
 Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells.
Fujikawa Y, Urano Y, …, Inoue H, Nagano T
J Am Chem Soc 2008 Nov 5 130(44):14533-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hening Lin
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

Tech Advance
Novel Drug Target
 Generating Arrays with High Content and Minimal Consumption of Functional Membrane Proteins.
Majd S, Mayer M
J Am Chem Soc 2008 Nov 1 0 [abstract on PubMed] [related articles] [full text]
Selected by | Ross Weatherman
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 A small molecule enhances RNA interference and promotes microRNA processing.
Shan G, Li Y, …, He C, Jin P
Nat Biotechnol 2008 Aug 26(8):933-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gabriele Varani
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Exploring RNA transcription and turnover in vivo by using click chemistry.
Jao CY, Salic A
Proc Natl Acad Sci U S A 2008 Oct 14 105(41):15779-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael B. Yaffe
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Importance of Direct Interactions with Lipids for the Function of the Mechanosensitive Channel MscL.
Powl AM, East JM, Lee AG
Biochemistry 2008 Oct 25 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Booth
Evaluated 13 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 The SIRT2 Deacetylase Regulates Autoacetylation of p300.
Black JC, Mosley A, …, Washburn M, Carey M
Mol Cell 2008 Nov 7 32(3):449-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 12 Nov 2008


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