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Must Read
F1000 Factor
6.0
New Finding
Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.
Montero J, Morales A, …, Colell A, Fernández-Checa JC
Cancer Res
2008 Jul 1
68
(13):5246-56 [
abstract on PubMed
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full text
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Selected by
| David Andrews
Evaluated 19 Nov 2008
Recommended
F1000 Factor
3.0
Confirmation
Hypothesis
New Finding
{alpha}- and {beta}- Monosaccharide Transport in Human Erythrocytes.
Carruthers A, Leitch J
Am J Physiol Cell Physiol
2008 Nov 5 [
abstract on PubMed
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full text
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Selected by
| Richard J Naftalin
Evaluated 18 Nov 2008
Must Read
F1000 Factor
6.0
New Finding
Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin.
Hennies HC, Kornak U, …, Wieacker P, Mundlos S
Nat Genet
2008 Nov 9 [
abstract on PubMed
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Selected by
| Peter McPherson
Evaluated 18 Nov 2008
Recommended
F1000 Factor
3.0
Tech Advance
Novel Drug Target
Generating Arrays with High Content and Minimal Consumption of Functional Membrane Proteins.
Majd S, Mayer M
J Am Chem Soc
2008 Nov 1
0
[
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Selected by
| Ross Weatherman
Evaluated 17 Nov 2008
Recommended
F1000 Factor
3.0
Confirmation
Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone.
Pochynyuk O, Bugaj V, …, Vallon V, Stockand JD
J Biol Chem
2008 Nov 3 [
abstract on PubMed
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Selected by
| William Welch
Evaluated 17 Nov 2008
Must Read
F1000 Factor
6.0
New Finding
Novel Drug Target
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
Du H, Guo L, …, Chen JX, Yan SD
Nat Med
2008 Oct
14
(10):1097-105 [
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Selected by
| Heinz Osiewacz
Evaluated 14 Nov 2008
Recommended
F1000 Factor
3.0
New Finding
Importance of Direct Interactions with Lipids for the Function of the Mechanosensitive Channel MscL.
Powl AM, East JM, Lee AG
Biochemistry
2008 Oct 25 [
abstract on PubMed
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FREE full text
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Selected by
| Ian Booth
Evaluated 13 Nov 2008
Recommended
F1000 Factor
3.0
New Finding
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase.
Brett CL, Plemel RL, …, Fields S, Merz AJ
J Cell Biol
2008 Sep 22
182
(6):1141-51 [
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Selected by
| Elizabeth Smythe
Evaluated 13 Nov 2008
Recommended
F1000 Factor
3.0
New Finding
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.
Rojas R, van Vlijmen T, …, van der Sluijs P, Bonifacino JS
J Cell Biol
2008 Nov 3
183
(3):513-26 [
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Selected by
| Michael Roth
Evaluated 12 Nov 2008
Must Read
F1000 Factor
6.0
Confirmation
New Finding
On the spontaneous emergence of cell polarity.
Altschuler SJ, Angenent SB, Wang Y, Wu LF
Nature
2008 Aug 14
454
(7206):886-9 [
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Selected by
| Carlos Dotti
Evaluated 11 Nov 2008
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