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Cell Adhesion
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Control of Gene Expression
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F1000 Factor 3.0

New Finding
 The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.
Lefevre P, Witham J, …, Cockerill PN, Bonifer C
Mol Cell 2008 Oct 10 32(1):129-39 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rob White
Evaluated 19 Nov 2008

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F1000 Factor 6.0

Hypothesis
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 Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
Yano M, Kuroda N, …, Mouri Y, Matsumoto M
J Exp Med 2008 Nov 17 [abstract on PubMed] [related articles] [full text]
Selected by | David Chaplin
Evaluated 19 Nov 2008

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F1000 Factor 3.0

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 Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.
Brown JM, Green J, …, Iborra FJ, Buckle VJ
J Cell Biol 2008 Sep 22 182(6):1083-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Shaw
Evaluated 18 Nov 2008

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F1000 Factor 6.0

Hypothesis
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 Glucose induces an autocrine activation of the Wnt/beta-catenin pathway in macrophage cell lines.
Anagnostou SH, Shepherd PR
Biochem J 2008 Dec 1 416(2):211-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alex Toker
Evaluated 18 Nov 2008

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F1000 Factor 3.0

Confirmation
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 PPAR{gamma} and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.
Lefterova MI, Zhang Y, …, Liu XS, Lazar MA
Genes Dev 2008 Nov 1 22(21):2941-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D. Sharrocks
Evaluated 18 Nov 2008

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F1000 Factor 3.0

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 Persistent epigenetic differences associated with prenatal exposure to famine in humans.
Heijmans BT, Tobi EW, …, Slagboom PE, Lumey LH
Proc Natl Acad Sci U S A 2008 Nov 4 105(44):17046-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wolf Reik
Evaluated 18 Nov 2008

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F1000 Factor 6.0

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 Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs.
Hirota K, Miyoshi T, …, Shibata T, Ohta K
Nature 2008 Nov 6 456(7218):130-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniel Reines
Evaluated 18 Nov 2008

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F1000 Factor 3.0

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 The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster.
Tucker NP, Hicks MG, …, Dixon R, Hutchings MI
PLoS ONE 2008 3(11):e3623 [abstract on PubMed] [related articles] [FREE full text]
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Evaluated 18 Nov 2008

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F1000 Factor 3.0

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 Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity.
Lee SS, Cha EY, …, Yeo CW, Shin JG
Hepatology 2008 Aug 48(2):635-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bruno Stieger
Evaluated 18 Nov 2008

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F1000 Factor 3.0

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 Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation.
Vitaliano-Prunier A, Menant A, …, Gwizdek C, Dargemont C
Nat Cell Biol 2008 Nov 10(11):1365-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bernhard Dichtl with André Halbach
Evaluated 17 Nov 2008


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