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F1000 Factor 3.0

Hypothesis
New Finding
Tech Advance
Spatial organization of a replicating bacterial chromosome.
Berlatzky IA, Rouvinski A, Ben-Yehuda S
Proc Natl Acad Sci U S A 2008 Sep 16 105(37):14136-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Linda Amos
Evaluated 10 Oct 2008

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F1000 Factor 6.0

Hypothesis
Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory.
Barrett RM, Wood MA
Learn Mem 2008 15(7):460-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Rapp
Evaluated 9 Oct 2008

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F1000 Factor 6.0

Hypothesis
New Finding
A new function of microtubule-associated protein tau: involvement in chromosome stability.
Rossi G, Dalprà L, …, Croci D, Tagliavini F
Cell Cycle 2008 Jun 7(12):1788-94 [abstract on PubMed] [related articles] [order article]
Selected by | George Perry
Evaluated 8 Oct 2008

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F1000 Factor 3.0

New Finding
Cyclin B-cdk1 controls pronuclear union in interphase.
Tachibana K, Hara M, Hattori Y, Kishimoto T
Curr Biol 2008 Sep 9 18(17):1308-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathon Pines
Evaluated 8 Oct 2008

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F1000 Factor 3.0

New Finding
Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis.
Hou YC, Chittaranjan S, …, McCall K, Gorski SM
J Cell Biol 2008 Sep 22 182(6):1127-39 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Harald Stenmark
Evaluated 8 Oct 2008

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F1000 Factor 6.0

Tech Advance
The Anchor-Away Technique: Rapid, Conditional Establishment of Yeast Mutant Phenotypes.
Haruki H, Nishikawa J, Laemmli UK
Mol Cell 2008 31:925-932 [full text]
Selected by | Mark Rose
Evaluated 3 Oct 2008

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F1000 Factor 3.0

New Finding
Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.
Wu D, Topper LM, Wilson TE
Genetics 2008 Mar 178(3):1237-49 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Michael Lieber
Evaluated 3 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes.
Tian D, Wang Q, …, Bergelson J, Chen JQ
Nature 2008 Sep 4 455(7209):105-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mohamed Noor
Evaluated 2 Oct 2008

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F1000 Factor 3.0

New Finding
Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.
Cataldo AM, Mathews PM, …, Gruenberg J, Nixon RA
Am J Pathol 2008 Aug 173(2):370-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | George Perry with Paula Moreira
Evaluated 2 Oct 2008

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F1000 Factor 6.0

Hypothesis
New Finding
Tech Advance
The Hsk1/Cdc7 Replication Kinase Regulates Origin Efficiency.
Patel PK, Kommajosyula N, …, Bechhoefer J, Rhind N
Mol Biol Cell 2008 Sep 17 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joel Huberman
Evaluated 2 Oct 2008


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