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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Controversial
 Hierarchical coding for sequential task events in the monkey prefrontal cortex.
Sigala N, Kusunoki M, …, Gaffan D, Duncan J
Proc Natl Acad Sci U S A 2008 Aug 19 105(33):11969-74 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Susan Courtney
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
 Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands.
Wray NR, Middeldorp CM, …, Martin NG, Boomsma DI
Arch Gen Psychiatry 2008 Jun 65(6):649-58 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Deary with Lorna Houlihan
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice.
Troy S, Soty M, …, Mithieux G, Andreelli F
Cell Metab 2008 Sep 8(3):201-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joel Elmquist with Kevin W. Williams
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Environmental novelty is signaled by reduction of the hippocampal theta frequency.
Jeewajee A, Lever C, …, O'Keefe J, Burgess N
Hippocampus 2008 18(4):340-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Edvard I. Moser with Dori Derdikman
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 A neural code for three-dimensional object shape in macaque inferotemporal cortex.
Yamane Y, Carlson ET, …, Wang Z, Connor CE
Nat Neurosci 2008 Nov 11(11):1352-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Earl Miller with Timothy Buschman
Evaluated 17 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
Novel Drug Target
 Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal.
Surget A, Saxe M, …, Hen R, Belzung C
Biol Psychiatry 2008 Aug 15 64(4):293-301 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Esther Sternberg with Marni Silverman
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Neural circuitry of stress-induced insomnia in rats.
Cano G, Mochizuki T, Saper CB
J Neurosci 2008 Oct 1 28(40):10167-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Luis de Lecea
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory.
Lubin FD, Roth TL, Sweatt JD
J Neurosci 2008 Oct 15 28(42):10576-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Manfred Gahr
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Controversial
Novel Drug Target
 Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression.
Ghia JE, Blennerhassett P, Collins SM
J Clin Invest 2008 Jun 118(6):2209-18 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ruud Buijs
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Phase resetting of the mammalian circadian clock by DNA damage.
Oklejewicz M, Destici E, …, Janssens R, van der Horst GT
Curr Biol 2008 Feb 26 18(4):286-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean Clairambault
Evaluated 14 Nov 2008


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