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F1000 Factor 3.0

Confirmation
Hypothesis
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 Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
Kvansakul M, Yang H, …, Huang DC, Colman PM
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Selected by | David Andrews
Evaluated 18 Nov 2008

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F1000 Factor 3.0

Hypothesis
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Selected by | Andy Groves
Evaluated 17 Nov 2008

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F1000 Factor 3.0

New Finding
 HSP27 is involved in the pathogenesis of kidney tubulointerstitial fibrosis.
Vidyasagar A, Reese S, …, Hullett D, Djamali A
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Selected by | Norma A. Bobadilla
Evaluated 17 Nov 2008


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F1000 Factor 6.0

New Finding
Novel Drug Target
 Rac activation and inactivation control plasticity of tumor cell movement.
Sanz-Moreno V, Gadea G, …, Sahai E, Marshall CJ
Cell 2008 Oct 31 135(3):510-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Klemke
Evaluated 13 Nov 2008

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F1000 Factor 3.0

New Finding
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Cell Stem Cell 2008 Nov 6 3(5):533-42 [abstract on PubMed] [related articles] [full text] [order article]
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Evaluated 13 Nov 2008

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F1000 Factor 9.0

Hypothesis
New Finding
 ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.
Wu X, Kodama A, Fuchs E
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F1000 Factor 6.0

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 Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms.
Barreiro O, Zamai M, …, Caiolfa VR, Sánchez-Madrid F
J Cell Biol 2008 Oct 27 [abstract on PubMed] [related articles] [full text]
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F1000 Factor 6.0

Tech Advance
 High resolution traction force microscopy based on experimental and computational advances.
Sabass B, Gardel ML, Waterman CM, Schwarz US
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Selected by | Ken Jacobson
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F1000 Factor 3.0

Confirmation
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 Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction.
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J Cell Biol 2008 Jul 28 182(2):395-410 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Chen with Ravi A. Desai
Evaluated 6 Nov 2008

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J Cell Sci 2008 May 15 121(Pt 10):1671-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Sherwood
Evaluated 6 Nov 2008


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