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Renal Biology
Renal Pharmacology
Renal, Fluid & Electrolyte Physiology

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Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis.
Kie JH, Kapturczak MH, …, Agarwal A, Hill-Kapturczak N
J Am Soc Nephrol 2008 Sep 19(9):1681-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christos Chatziantoniou with Christos Chadjichristos
Evaluated 1 Oct 2008


Exceptional
F1000 Factor 9.0

New Finding
 TMEM16A confers receptor-activated calcium-dependent chloride conductance.
Yang YD, Cho H, …, Shin YK, Oh U
Nature 2008 Aug 24 [abstract on PubMed] [related articles] [full text]
Selected by | Bernd Nilius
Evaluated 25 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Long-term safety, tolerability, and efficacy of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder.
Homma Y, Yamaguchi O
Int J Urol 2008 Aug 28 [abstract on PubMed] [related articles] [full text]
Selected by | Rodolfo Testa
Evaluated 24 Sep 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Oscillating Cortical Thick Ascending Limb Cells at the Juxtaglomerular Apparatus.
Komlosi P, Banizs B, …, Zhang ZR, Bell PD
J Am Soc Nephrol 2008 Jun 18 [abstract on PubMed] [related articles] [full text]
Selected by | Janos Peti-Peterdi
Evaluated 24 Sep 2008


Recommended
F1000 Factor 3.0

New Finding
 Renal D3 dopamine receptor stimulation induces natriuresis by endothelin B receptor interactions.
Zeng C, Asico LD, …, Eisner GM, Jose PA
Kidney Int 2008 Sep 74(6):750-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Pollock with Erika Boesen
Evaluated 19 Sep 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Adaptive mutations in the signal peptide of the type 1 fimbrial adhesin of uropathogenic Escherichia coli.
Ronald LS, Yakovenko O, …, Thomas WE, Sokurenko EV
Proc Natl Acad Sci U S A 2008 Aug 5 105(31):10937-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Esther Bullitt
Evaluated 11 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
 Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation.
Carvajal G, Rodríguez-Vita J, …, Mezzano SA, Ruiz-Ortega M
Kidney Int 2008 Sep 74(5):585-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Norma A. Bobadilla
Evaluated 5 Sep 2008

Must Read
F1000 Factor 4.8

Hypothesis
New Finding
Novel Drug Target
 TRPP2 and TRPV4 form a polymodal sensory channel complex.
Köttgen M, Buchholz B, …, Kuehn EW, Walz G
J Cell Biol 2008 Aug 11 182(3):437-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jens Leipziger with Helle A. Praetorius / Patrick Delmas
First evaluation 4 Sep 2008 | Latest evaluation 24 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro.
Wang H, Yoshiko Y, …, Aubin JE, Maeda N
J Bone Miner Res 2008 Jun 23(6):939-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Eleanor Lederer
Evaluated 3 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
Refutation
 Do mammals make all their own inositol hexakisphosphate?
Letcher AJ, Schell MJ, Irvine RF
Biochem J 2008 Aug 6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Steve Shears
Evaluated 2 Sep 2008


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