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Recommended
F1000 Factor
3.0
New Finding
Unprecedented immunosuppressive polyketides from Daldinia eschscholzii, a mantis-associated fungus.
Zhang YL, Ge HM, …, Song YC, Tan RX
Angew Chem Int Ed Engl
2008
47
(31):5823-6 [
abstract on PubMed
] [
related articles
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full text
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Selected by
| Dennis Hall
Evaluated 29 Aug 2008
Recommended
F1000 Factor
3.0
Confirmation
New Finding
Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice.
Rensen SS, Niessen PM, …, De Mey JG, van Eys GJ
Circulation
2008 Aug 19
118
(8):828-36 [
abstract on PubMed
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Selected by
| Giulio Gabbiani
Evaluated 29 Aug 2008
Must Read
F1000 Factor
6.0
Confirmation
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study.
Larson RA, Druker BJ, …, Wang Y, IRIS (International Randomized Interferon vs STI571) Study Group
Blood
2008 Apr 15
111
(8):4022-8 [
abstract on PubMed
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Selected by
| Susan Bates
Evaluated 28 Aug 2008
Recommended
F1000 Factor
3.0
Hypothesis
New Finding
Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia.
Picard S, Titier K, …, Molimard M, Mahon FX
Blood
2007 Apr 15
109
(8):3496-9 [
abstract on PubMed
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Selected by
| Susan Bates
Evaluated 28 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Upregulation of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinases in rapid atrial pacing-induced atrial fibrillation.
Chen CL, Huang SK, …, Wen CH, Lin CS
J Mol Cell Cardiol
2008 Jul 23 [
abstract on PubMed
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Selected by
| Anthony Dart
Evaluated 28 Aug 2008
Exceptional
F1000 Factor
9.0
New Finding
The macromolecular assembly of pathogen-recognition receptors is impelled by serine proteases, via their complement control protein modules.
Le Saux A, Ng PM, …, Ho B, Ding JL
J Mol Biol
2008 Mar 28
377
(3):902-13 [
abstract on PubMed
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Selected by
| John Atkinson
Evaluated 26 Aug 2008
Recommended
F1000 Factor
3.0
Confirmation
New Finding
Long-term results of carotid stenting versus endarterectomy in high-risk patients.
Gurm HS, Yadav JS, …, Cutlip DE, SAPPHIRE Investigators
N Engl J Med
2008 Apr 10
358
(15):1572-9 [
abstract on PubMed
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Selected by
| Rafael Beyar
Evaluated 21 Aug 2008
Recommended
F1000 Factor
3.0
Hypothesis
New Finding
Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
Archer SL, Gragasin FS, …, Falck JR, Michelakis ED
Circulation
2003 Feb 11
107
(5):769-76 [
abstract on PubMed
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FREE full text
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Selected by
| Andreas Deussen
Evaluated 21 Aug 2008
Must Read
F1000 Factor
4.8
New Finding
Tech Advance
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators.
Stoilov P, Lin CH, …, Nikolic J, Black DL
Proc Natl Acad Sci U S A
2008 Aug 12
105
(32):11218-23 [
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Selected by
| Anne Baranger / Sui Huang
First evaluation 20 Aug 2008 | Latest evaluation 26 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney.
Toma I, Kang JJ, …, Meer E, Peti-Peterdi J
J Clin Invest
2008 Jul
118
(7):2526-34 [
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Selected by
| Matthew Breyer
Evaluated 20 Aug 2008
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