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Control of Gene Expression
Nuclear Structure & Function

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F1000 Factor 3.0

Tech Advance
 Site-specific crosslinking of human microRNPs to RNA targets.
Kirino Y, Mourelatos Z
RNA 2008 Aug 21 [abstract on PubMed] [related articles] [full text]
Selected by | Kevin J. Luebke
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57.
Mackay DJ, Callaway JL, …, Robinson DO, Temple IK
Nat Genet 2008 Aug 40(8):949-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wolf Reik
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Ripples from neighbouring transcription.
Ebisuya M, Yamamoto T, Nakajima M, Nishida E
Nat Cell Biol 2008 Aug 10 [abstract on PubMed] [related articles] [full text]
Selected by | Andrew D. Sharrocks
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 A Rad51 presynaptic filament is sufficient to capture nucleosomal homology during recombinational repair of a DNA double-strand break.
Sinha M, Peterson CL
Mol Cell 2008 Jun 20 30(6):803-10 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Antony Carr
Evaluated 29 Aug 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The transcriptional program underlying the physiology of clostridial sporulation.
Jones SW, Paredes CJ, …, Senger RS, Papoutsakis ET
Genome Biol 2008 Jul 16 9(7):R114 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Juergen Wiegel
Evaluated 28 Aug 2008

Must Read
F1000 Factor 6.0

New Finding
 Nucleotide excision repair driven by the dissociation of CAK from TFIIH.
Coin F, Oksenych V, …, Blattner C, Egly JM
Mol Cell 2008 Jul 11 31(1):9-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Pengbo Zhou
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Controversial
 The H19 locus acts in vivo as a tumor suppressor.
Yoshimizu T, Miroglio A, …, Jammes H, Dandolo L
Proc Natl Acad Sci U S A 2008 Aug 21 [abstract on PubMed] [related articles] [full text]
Selected by | Wolf Reik
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Retinoblastoma and Its Binding Partner MSI1 Control Imprinting in Arabidopsis.
Jullien PE, Mosquna A, …, Ohad N, Berger F
PLoS Biol 2008 Aug 12 6(8):e194 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Wolf Reik
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances.
Wang SS, Kamphuis W, …, Zhou JN, Swaab DF
Mol Psychiatry 2008 Aug 13(8):786-99, 741 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Seckl
Evaluated 28 Aug 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Regulation of a eukaryotic gene by GTP-dependent start site selection and transcription attenuation.
Kuehner JN, Brow DA
Mol Cell 2008 Jul 25 31(2):201-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dinah Singer
Evaluated 27 Aug 2008


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