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F1000 Factor 3.0

Tech Advance
 Antimicrobial Surfaces through Natural Product Hybrids.
Wach JY, Bonazzi S, Gademann K
Angew Chem Int Ed Engl 2008 Jul 31 47(37):7123-7126 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Günter Mayer
Evaluated 29 Aug 2008

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
 Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.
Yu X, Tsibane T, …, Basler CF, Crowe Jr JE
Nature 2008 Aug 17 [abstract on PubMed] [related articles] [full text]
Selected by | Adolfo Garcia-Sastre
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

Tech Advance
 Deployable laboratory response to emergence of melioidosis in central Sri Lanka.
Inglis TJ, Merritt A, …, Thevanesam V, McInnes R
J Clin Microbiol 2008 Aug 20 [abstract on PubMed] [related articles] [full text]
Selected by | Gary Lum
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Controversial
 A Role for Confined Water in Chaperonin Function.
England JL, Lucent D, Pande VS
J Am Chem Soc 2008 Aug 19 0 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Shea
Evaluated 29 Aug 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Tech Advance
 eSGA: E. coli synthetic genetic array analysis.
Butland G, Babu M, …, Greenblatt JF, Emili A
Nat Methods 2008 Aug 1 [abstract on PubMed] [related articles] [full text]
Selected by | Mohan Balasubramanian with Mithilesh Mishra and Ramanujam Srinivasan
Evaluated 29 Aug 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Tech Advance
Novel Drug Target
 High-throughput, quantitative analyses of genetic interactions in E. coli.
Typas A, Nichols RJ, …, Krogan NJ, Gross CA
Nat Methods 2008 Aug 1 [abstract on PubMed] [related articles] [full text]
Selected by | Mohan Balasubramanian with Mithilesh Mishra and Ramanujam Srinivasan
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Lowering of 5-nitroimidazole's mutagenicity: Towards optimal antiparasitic pharmacophore.
Crozet MD, Botta C, …, De Méo M, Vanelle P
Eur J Med Chem 2008 May 27 [abstract on PubMed] [related articles] [full text]
Selected by | Jacqueline Upcroft
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation.
Hava DL, van der Wel N, …, Peters PJ, Brenner MB
Proc Natl Acad Sci U S A 2008 Aug 12 105(32):11281-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sergio Grinstein with Ronald Flannagan
Evaluated 28 Aug 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The transcriptional program underlying the physiology of clostridial sporulation.
Jones SW, Paredes CJ, …, Senger RS, Papoutsakis ET
Genome Biol 2008 Jul 16 9(7):R114 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Juergen Wiegel
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

Confirmation
 The molecular basis of functional bacterial amyloid polymerization and nucleation.
Wang X, Hammer ND, Chapman MR
J Biol Chem 2008 Aug 1 283(31):21530-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Lynn with W. Seth Childers
Evaluated 27 Aug 2008


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