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Recommended
F1000 Factor 3.0

Confirmation
New Finding
 KANADI1 regulates adaxial-abaxial polarity in Arabidopsis by directly repressing the transcription of ASYMMETRIC LEAVES2.
Wu G, Lin WC, …, Springer PS, Kerstetter RA
Proc Natl Acad Sci U S A 2008 Oct 21 105(42):16392-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jennifer Fletcher with Chan Man Ha
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.
Lefevre P, Witham J, …, Cockerill PN, Bonifer C
Mol Cell 2008 Oct 10 32(1):129-39 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rob White
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
Yano M, Kuroda N, …, Mouri Y, Matsumoto M
J Exp Med 2008 Nov 17 [abstract on PubMed] [related articles] [full text]
Selected by | David Chaplin
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

Tech Advance
 The transition from differential equations to Boolean networks: a case study in simplifying a regulatory network model.
Davidich M, Bornholdt S
J Theor Biol 2008 Dec 7 255(3):269-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Maini
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Flowering-time genes modulate meristem determinacy and growth form in Arabidopsis thaliana.
Melzer S, Lens F, …, Rohde A, Beeckman T
Nat Genet 2008 Nov 9 [abstract on PubMed] [related articles] [full text]
Selected by | Christian Hardtke
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Cloning and characterization of naringenin 8-prenyltransferase, a flavonoid-specific prenyltransferase of Sophora flavescens.
Sasaki K, Mito K, …, Yamamoto H, Yazaki K
Plant Physiol 2008 Mar 146(3):1075-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lloyd W. Sumner
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.
Brown JM, Green J, …, Iborra FJ, Buckle VJ
J Cell Biol 2008 Sep 22 182(6):1083-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Shaw
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Glucose induces an autocrine activation of the Wnt/beta-catenin pathway in macrophage cell lines.
Anagnostou SH, Shepherd PR
Biochem J 2008 Dec 1 416(2):211-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alex Toker
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 PPAR{gamma} and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.
Lefterova MI, Zhang Y, …, Liu XS, Lazar MA
Genes Dev 2008 Nov 1 22(21):2941-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D. Sharrocks
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
 Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands.
Wray NR, Middeldorp CM, …, Martin NG, Boomsma DI
Arch Gen Psychiatry 2008 Jun 65(6):649-58 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Deary with Lorna Houlihan
Evaluated 18 Nov 2008


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