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 Sections & Scopes for Chemical Biology   [ printable version Printable version ]

SECTION
SCOPE
BiocatalysisBiocatalysis
Enzyme complexes
Enzyme engineering
Enzyme mechanisms
Metabolic engineering
Metabolic pathways
Natural products biosynthesis
Novel enzyme cofactors
Radicals
Regulation

Bioinorganic ChemistryBiominerals & biomineralization
Chemistry of NO
Electron transport & oxygen metabolism
Hydrolytic & water chemistry
Metal ion uptake, storage, & metabolism
Metal-dependent sensors/regulators
Metalloenzymes with radical intermediates
Metal-nucleic acid chemistry
Metals & medicine
Molybdenum & tungsten
Nitrogen, sulfur, hydrogen, & carbon metabolism

Biomimetic ChemistryArtificial catalysts
Chemical models for biological processes
Cofactor models & surrogates
Dendrimers
Designed complexes & arrays
Micelles, liposomes, membranes
Molecular computing
Molecular devices & sensors
Reaction networks
Receptors & recognition
Transport & channel design

Chemical Biology of the CellCell surface engineering
Chemical genetics
Intracellular monitoring
Metabolic pathway engineering
Modulation of signal transduction
Protein-protein interactions
Receptor-ligand interactions
Sensors & imaging
Single cell metabolite assays
Transcriptional regulation & control

Directed Molecular EvolutionAptamers
Bioprospecting & enzyme discovery
Catalytic antibodies
Combinatorial biosynthesis
Directed evolution
Generation of diversity
In vitro selection
Molecular ecology
Phage/ribosome display
Theoretical foundations of molecular evolution

Drug Discovery & DesignCombinatorial chemistry
Drug approval & regulatory aspects
High-throughput screening
In-silico drug design
Medicinal chemistry
Pharmacoeconomics
Structure-activity relationships
Target discovery & validation

Macromolecular ChemistryCarbohydrates (including glycosaminoglycans & polysaccharides)
Chemical synthesis of natural & non-natural proteins
Glycoproteins & glycolipids
Lipids, liposomes, membranes
Macromolecular arrays, synthesis & analysis of macromolecular arrays (AFM, SPR, etc., new patterning methods, etc.)
Macromolecular conjugates
Microarrays
Non-natural biologically active polymers
Non-natural glycoconjugates & glycoprotein analogs
Nucleic acid analogs
Nucleic acid catalysis
Protein modification
RNA/DNA folding

Protein Chemistry & ProteomicsAnalysis of protein-protein interactions
Folding
Modification
Novel drug targets
Protein arrays
Protein design
Protein expression & secretion
Protein expression mapping
Protein separation & identification

Small Molecule ChemistryCombinatorial chemistry
Discovery of natural products
Lead optimisation
Natural product biosynthesis
Novel enzyme co-factors & mechanistic probes
Screening technologies
Structure based drug design



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