Amy Barrios sponsors free access to F1000 for University of Rosario, Rosario, Argentina. Supporting F1000's initiative to make itself available to scientists in all countries, including free access to developing countries (more details).

A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells. Boivin B, Zhang S, …, Zhang ZY, Tonks NK Proc Natl Acad Sci U S A 2008 Jul 22 105(29):9959-64 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 27 Aug 2008 Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype. Myers MC, Shah PP, …, Smith AB, Huryn DM Bioorg Med Chem Lett 2008 Jun 15 18(12):3646-51 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios with Divya Krishnamurthy Evaluated 1 Aug 2008 Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases. Liu S, Zhou B, …, Wu L, Zhang ZY J Am Chem Soc 2008 Jul 2 130(26):8251-60 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Dehua Pei / Hening Lin / Amy Barrios with Divya Krishnamurthy Evaluated 17 Jul 2008 Designing better coumarin-based fluorogenic substrates for PTP1B. Holmes CP, Macher N, …, Jang L, Irvine JD Bioorg Med Chem Lett 2008 Jun 1 18(11):3382-5 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 16 Jun 2008 Fluorescence spectroscopic profiling of compound libraries. Simeonov A, Jadhav A, …, Auld DS, Inglese J J Med Chem 2008 Apr 24 51(8):2363-71 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Ron Magolda / Amy Barrios Evaluated 19 May 2008 Near-infrared light activated release of nitric oxide from designed photoactive manganese nitrosyls: strategy, design, and potential as NO donors. Eroy-Reveles AA, Leung Y, …, Olmstead MM, Mascharak PK J Am Chem Soc 2008 Apr 2 130(13):4447-58 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 23 Apr 2008 New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications. Sannella AR, Casini A, …, Majori G, Severini C FEBS Lett 2008 Mar 19 582(6):844-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 19 Mar 2008 Cu(I) recognition via cation-pi and methionine interactions in CusF. Xue Y, Davis AV, …, Penner-Hahn JE, O'Halloran TV Nat Chem Biol 2008 Feb 4(2):107-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 15 Feb 2008 Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway. Saggioro D, Rigobello MP, …, Fregona D, Bindoli A Chem Biol 2007 Oct 14(10):1128-39 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 15 Jan 2008 Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. Yu X, Sun JP, …, Hudmon A, Zhang ZY Proc Natl Acad Sci U S A 2007 Dec 11 104(50):19767-72 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 19 Dec 2007 A predictably selective aliphatic C-H oxidation reaction for complex molecule synthesis. Chen MS, White MC Science 2007 Nov 2 318(5851):783-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 14 Nov 2007 A genetically encoded fluorescent amino acid. Wang J, Xie J, Schultz PG J Am Chem Soc 2006 Jul 12 128(27):8738-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 16 Oct 2007 Structure of the zinc transporter YiiP. Lu M, Fu D Science 2007 Sep 21 317(5845):1746-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Poul Nissen / Amy Barrios / Ian Booth Evaluated 5 Sep 2007 Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB. Soellner MB, Rawls KA, …, Alber T, Ellman JA J Am Chem Soc 2007 Aug 8 129(31):9613-5 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Robert Garbaccio / Amy Barrios / Robert Copeland / David Waugh Evaluated 13 Aug 2007 Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products. Gracanin M, Davies MJ Free Radic Biol Med 2007 May 15 42(10):1543-51 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 5 Jul 2007 Substrate profiling of protein tyrosine phosphatase PTP1B by screening a combinatorial peptide library. Garaud M, Pei D J Am Chem Soc 2007 May 2 129(17):5366-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 11 Jun 2007 Redox regulation of protein tyrosine phosphatase 1B by peroxymonophosphate (=O3POOH). LaButti JN, Chowdhury G, Reilly TJ, Gates KS J Am Chem Soc 2007 May 2 129(17):5320-1 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 17 May 2007 Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S. Weidauer E, Yasuda Y, …, James MN, Brömme D Biol Chem 2007 Mar 388(3):331-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 16 Apr 2007 Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B. Yudushkin IA, Schleifenbaum A, …, Schultz C, Bastiaens PI Science 2007 Jan 5 315(5808):115-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Kermit Carraway / Amy Barrios / Dafna Bar-Sagi / Karen Allen Evaluated 14 Mar 2007 Bacterial sensing of and resistance to gold salts. Checa SK, Espariz M, …, Spinelli SV, Soncini FC Mol Microbiol 2007 Mar 63(5):1307-18 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 8 Feb 2007 Phosphopeptide modification and enrichment by oxidation-reduction condensation. Warthaka M, Karwowska-Desaulniers P, Pflum MK ACS Chem Biol 2006 Dec 20 1(11):697-701 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 3 Jan 2007 Design and characterization of an active site selective caspase-3 transnitrosating agent. Mitchell DA, Morton SU, Marletta MA ACS Chem Biol 2006 Nov 21 1(10):659-65 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 20 Dec 2006 A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. Whitnall M, Howard J, Ponka P, Richardson DR Proc Natl Acad Sci U S A 2006 Oct 3 103(40):14901-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios Evaluated 6 Nov 2006 Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex. Barnard PJ, Wedlock LE, …, Skelton BW, Steer JH Angew Chem Int Ed Engl 2006 Sep 11 45(36):5966-70 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 4 Oct 2006 Global analysis of protein tyrosine phosphatase activity with ultra-sensitive fluorescent probes. Kumar S, Zhou B, …, Wang WQ, Zhang ZY J Proteome Res 2006 Aug 5(8):1898-905 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 29 Aug 2006 Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori. Ge R, Watt RM, …, Huang JD, Sun H Biochem J 2006 Jan 1 393(Pt 1):285-93 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios Evaluated 11 Aug 2006 Mechanism of inhibition of protein-tyrosine phosphatases by disodium aurothiomalate. Wang Q, Janzen N, Ramachandran C, Jirik F Biochem Pharmacol 1997 Sep 15 54(6):703-11 [abstract on PubMed] [related articles] [order article] Selected by | Amy Barrios Evaluated 10 Jul 2006 Measuring picomolar intracellular exchangeable zinc in PC-12 cells using a ratiometric fluorescence biosensor. Bozym RA, Thompson RB, Stoddard AK, Fierke CA ACS Chem Biol 2006 Mar 17 1(2):103-11 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Anthony Czarnik / Amy Barrios Evaluated 8 Jun 2006 Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases. Urig S, Fritz-Wolf K, …, Davioud-Charvet E, Becker K Angew Chem Int Ed Engl 2006 Mar 13 45(12):1881-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 12 May 2006 Noble metals strip peptides from class II MHC proteins. De Wall SL, Painter C, …, Stern LJ, DeDecker BS Nat Chem Biol 2006 Apr 2(4):197-201 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Robert Booth / Elizabeth Mellins / Amy Barrios / Paul Roche Evaluated 6 Apr 2006 Light-activated destruction of cancer cell nuclei by platinum diazide complexes. Bednarski PJ, Grünert R, …, Mackay FS, Sadler PJ Chem Biol 2006 Jan 13(1):61-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 7 Feb 2006 Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions. Larabee JL, Hocker JR, Hanas JS Chem Res Toxicol 2005 Dec 18(12):1943-54 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 10 Jan 2006 Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Vang T, Congia M, …, Mustelin T, Bottini N Nat Genet 2005 Dec 37(12):1317-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Robert Booth / Amy Barrios Evaluated 12 Dec 2005 Urea decomposition facilitated by a urease model complex: a theoretical investigation. Beddie C, Webster CE, Hall MB Dalton Trans 2005 Nov 7 (21):3542-51 [abstract on PubMed] [related articles] [full text] Selected by | Amy Barrios Evaluated 7 Nov 2005 Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Blum G, Mullins SR, …, Sloane BF, Bogyo M Nat Chem Biol 2005 Sep 1(4):203-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 4 Oct 2005 The burden borne by urease. Callahan BP, Yuan Y, Wolfenden R J Am Chem Soc 2005 Aug 10 127(31):10828-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 26 Aug 2005 Crystallographic and spectroscopic evidence for high affinity binding of FeEDTA(H2O)- to the periplasmic nickel transporter NikA. Cherrier MV, Martin L, …, Gaillard J, Fontecilla-Camps JC J Am Chem Soc 2005 Jul 20 127(28):10075-82 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Michael Maroney / Amy Barrios / Nitaya Thammapalerd Evaluated 26 Jul 2005 Structural bioinformatics-based design of selective, irreversible kinase inhibitors. Cohen MS, Zhang C, Shokat KM, Taunton J Science 2005 May 27 308(5726):1318-21 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios / Alfred Wittinghofer / Matthew Bogyo Evaluated 16 Jun 2005 A fluorogenic dye activated by the staudinger ligation. Lemieux GA, De Graffenried CL, Bertozzi CR J Am Chem Soc 2003 Apr 23 125(16):4708-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 23 May 2005 Formation of a carbon-carbon triple bond by coupling reactions in aqueous solution. Bino A, Ardon M, Shirman E Science 2005 Apr 8 308(5719):234-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios Evaluated 19 Apr 2005 Allosteric inhibition of protein tyrosine phosphatase 1B. Wiesmann C, Barr KJ, …, McDowell RS, Hansen SK Nat Struct Mol Biol 2004 Aug 11(8):730-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Stevan Hubbard / Celerino Abad-Zapatero / Wolfgang Jahnke / Zhong-Yin Zhang / Amy Barrios Evaluated 11 Apr 2005 Allele-specific inhibitors of protein tyrosine phosphatases. Hoffman HE, Blair ER, Johndrow JE, Bishop AC J Am Chem Soc 2005 Mar 9 127(9):2824-5 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 14 Mar 2005 Characterization of a plant, tyrosine-specific phosphatase of the aspartyl class. Rayapureddi JP, Kattamuri C, Chan FH, Hegde RS Biochemistry 2005 Jan 18 44(2):751-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 7 Mar 2005 Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Jiang T, Olson ES, …, Jennings PA, Tsien RY Proc Natl Acad Sci U S A 2004 Dec 21 101(51):17867-72 [abstract on PubMed] [related articles] [FREE full text] Selected by | Kees Jalink / Amy Barrios / Wen-hong Li Evaluated 7 Feb 2005 Differential oxidation of protein-tyrosine phosphatases. Groen A, Lemeer S, …, Slijper M, den Hertog J J Biol Chem 2005 Mar 18 280(11):10298-304 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios Evaluated 17 Jan 2005 New water-soluble phosphines as reductants of peptide and protein disulfide bonds: reactivity and membrane permeability. Cline DJ, Redding SE, …, Schneider JP, Thorpe C Biochemistry 2004 Dec 7 43(48):15195-203 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 10 Dec 2004 A linear, O-coordinated eta1-CO2 bound to uranium. Castro-Rodriguez I, Nakai H, …, Rheingold AL, Meyer K Science 2004 Sep 17 305(5691):1757-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios Evaluated 23 Nov 2004 Activity-based probes for protein tyrosine phosphatases. Kumar S, Zhou B, …, Huang Z, Zhang ZY Proc Natl Acad Sci U S A 2004 May 25 101(21):7943-8 [abstract on PubMed] [related articles] [FREE full text] Selected by | Matthew Bogyo / Amy Barrios Evaluated 23 Nov 2004 Methanobactin, a copper-acquisition compound from methane-oxidizing bacteria. Kim HJ, Graham DW, …, Asunskis D, Sherwood PM Science 2004 Sep 10 305(5690):1612-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios Evaluated 25 Oct 2004 Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions. Pia Rigobello M, Messori L, …, Scutari G, Bindoli A J Inorg Biochem 2004 Oct 98(10):1634-41 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 7 Oct 2004 Discovery of an allosteric site in the caspases. Hardy JA, Lam J, …, O'Brien T, Wells JA Proc Natl Acad Sci U S A 2004 Aug 24 101(34):12461-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios / Yigong Shi Evaluated 27 Aug 2004 New beginnings for matrix metalloproteinase inhibitors: identification of high-affinity zinc-binding groups. Puerta DT, Lewis JA, Cohen SM J Am Chem Soc 2004 Jul 14 126(27):8388-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 23 Jul 2004 Activity-based probes for the proteomic profiling of metalloproteases. Saghatelian A, Jessani N, …, Humphrey M, Cravatt BF Proc Natl Acad Sci U S A 2004 Jul 6 101(27):10000-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Amy Barrios / Matthew Bogyo Evaluated 20 Jul 2004 NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system. Di Lello P, Benison GC, …, Legault P, Omichinski JG Biochemistry 2004 Jul 6 43(26):8322-32 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Amy Barrios Evaluated 9 Jul 2004

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