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Stephen Busby
University of Birmingham, United Kingdom

Faculty Member: Microbiology > Microbial Physiology & Metabolism [ since 6 July 2001 ]
[ Evaluations ]
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Evaluations

Sensing of 5' monophosphate by Escherichia coli RNase G can significantly enhance association with RNA and stimulate the decay of functional mRNA transcripts in vivo.
Jourdan SS, McDowall KJ
Mol Microbiol 2008 Jan 67(1):102-115 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 29 Jan 2008

Intracellular levels and activity of PvdS, the major iron starvation sigma factor of Pseudomonas aeruginosa.
Tiburzi F, Imperi F, Visca P
Mol Microbiol 2007 Dec 7 67(1):213-227 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 29 Jan 2008

The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal.
Deana A, Celesnik H, Belasco JG
Nature 2008 Jan 17 451(7176):355-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Gourse / Stephen Busby
Evaluated 29 Jan 2008

SlyA and H-NS regulate transcription of the Escherichia coli K5 capsule gene cluster, and expression of slyA in Escherichia coli is temperature-dependent, positively autoregulated, and independent of H-NS.
Corbett D, Bennett HJ, …, Green J, Roberts IS
J Biol Chem 2007 Nov 16 282(46):33326-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 21 Nov 2007

The AraC/XylS regulator TxtR modulates thaxtomin biosynthesis and virulence in Streptomyces scabies.
Joshi MV, Bignell DR, …, Gibson DM, Loria R
Mol Microbiol 2007 Nov 66(3):633-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 15 Nov 2007

Transketolase A, an enzyme in central metabolism, derepresses the marRAB multiple antibiotic resistance operon of Escherichia coli by interaction with MarR.
Domain F, Bina XR, Levy SB
Mol Microbiol 2007 Oct 66(2):383-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 30 Oct 2007

Microarray analysis of Mu transposition in Salmonella enterica, serovar Typhimurium: transposon exclusion by high-density DNA binding proteins.
Manna D, Porwollik S, …, Tan R, Higgins NP
Mol Microbiol 2007 Oct 66(2):315-28 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 30 Oct 2007

High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes.
Lang B, Blot N, …, Babu MM, Travers A
Nucleic Acids Res 2007 35(18):6330-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 19 Oct 2007

Activation of yeaR-yoaG operon transcription by the nitrate-responsive regulator NarL is independent of oxygen- responsive regulator Fnr in Escherichia coli K-12.
Lin HY, Bledsoe PJ, Stewart V
J Bacteriol 2007 Nov 189(21):7539-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 6 Sep 2007

Transcription activation mediated by a cyclic AMP receptor protein from Thermus thermophilus HB8.
Shinkai A, Kira S, …, Kuramitsu S, Yokoyama S
J Bacteriol 2007 May 189(10):3891-901 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 24 Apr 2007

The bacteriophage lambdaQ anti-terminator protein regulates late gene expression as a stable component of the transcription elongation complex.
Deighan P, Hochschild A
Mol Microbiol 2007 Feb 63(3):911-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles J. Dorman / Stephen Busby
Evaluated 12 Feb 2007

Selection for unequal densities of sigma70 promoter-like signals in different regions of large bacterial genomes.
Huerta AM, Francino MP, Morett E, Collado-Vides J
PLoS Genet 2006 Nov 10 2(11):e185 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 28 Nov 2006

Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation.
Dame RT, Noom MC, Wuite GJ
Nature 2006 Nov 16 444(7117):387-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Ladbury / Stephen Busby / Charles J. Dorman
Evaluated 27 Nov 2006

Unexpected twist: harnessing the energy in positive supercoils to control telomere resolution.
Bankhead T, Kobryn K, Chaconas G
Mol Microbiol 2006 Nov 62(3):895-905 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 16 Nov 2006

EilA, a HilA-like regulator in enteroaggregative Escherichia coli.
Sheikh J, Dudley EG, …, Suleman A, Nataro JP
Mol Microbiol 2006 Jul 61(2):338-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 14 Aug 2006

Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome.
Gao J, Lee K, …, Cohen SN, Georgiou G
Mol Microbiol 2006 Jul 61(2):394-406 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 14 Aug 2006

Insights into transcriptional regulation and sigma competition from an equilibrium model of RNA polymerase binding to DNA.
Grigorova IL, Phleger NJ, Mutalik VK, Gross CA
Proc Natl Acad Sci U S A 2006 Apr 4 103(14):5332-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 13 Apr 2006

The integration host factor (IHF) integrates stationary-phase and virulence gene expression in Salmonella enterica serovar Typhimurium.
Mangan MW, Lucchini S, …, Hinton JC, Dorman CJ
Mol Microbiol 2006 Mar 59(6):1831-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 27 Mar 2006

Imaging OmpR localization in Escherichia coli.
Batchelor E, Goulian M
Mol Microbiol 2006 Mar 59(6):1767-78 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby / Charles J. Dorman
Evaluated 27 Mar 2006

Identification of the central quorum sensing regulator of virulence in the enteric phytopathogen, Erwinia carotovora: the VirR repressor.
Burr T, Barnard AM, …, Simpson NJ, Salmond GP
Mol Microbiol 2006 Jan 59(1):113-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 31 Jan 2006

Protein-induced DNA bending clarifies the architectural organization of the sigma54-dependent glnAp2 promoter.
Huo YX, Tian ZX, …, Wang YP, Kolb A
Mol Microbiol 2006 Jan 59(1):168-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 31 Jan 2006

Multiple functions of l0036 in the regulation of the pathogenicity island of enterohaemorrhagic Escherichia coli O157:H7.
Tsai NP, Wu YC, …, Tzeng CM, Syu WJ
Biochem J 2006 Jan 15 393(Pt 2):591-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 20 Jan 2006

A reassessment of the FNR regulon and transcriptomic analysis of the effects of nitrate, nitrite, NarXL, and NarQP as Escherichia coli K12 adapts from aerobic to anaerobic growth.
Constantinidou C, Hobman JL, …, Cole JA, Overton TW
J Biol Chem 2006 Feb 24 281(8):4802-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby / David Richardson
Evaluated 10 Jan 2006

A genetic selection for supercoiling mutants of Escherichia coli reveals proteins implicated in chromosome structure.
Hardy CD, Cozzarelli NR
Mol Microbiol 2005 Sep 57(6):1636-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 5 Oct 2005

A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor.
Rickman L, Scott C, …, Green J, Buxton RS
Mol Microbiol 2005 Jun 56(5):1274-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 27 May 2005

An altered-specificity DNA-binding mutant of Escherichia coli sigma70 facilitates the analysis of sigma70 function in vivo.
Gregory BD, Nickels BE, Darst SA, Hochschild A
Mol Microbiol 2005 Jun 56(5):1208-19 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 26 May 2005

Frameshifting by transcriptional slippage is involved in production of MxiE, the transcription activator regulated by the activity of the type III secretion apparatus in Shigella flexneri.
Penno C, Sansonetti P, Parsot C
Mol Microbiol 2005 Apr 56(1):204-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 19 Apr 2005

Evidence that Bacillus catabolite control protein CcpA interacts with RNA polymerase to inhibit transcription.
Kim JH, Yang YK, Chambliss GH
Mol Microbiol 2005 Apr 56(1):155-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 19 Apr 2005

The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes, increases DNA-binding affinity by stabilizing the HTH motif.
Eiting M, Hagelüken G, Schubert WD, Heinz DW
Mol Microbiol 2005 Apr 56(2):433-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 19 Apr 2005

Bacterial transcription elongation factors: new insights into molecular mechanism of action.
Borukhov S, Lee J, Laptenko O
Mol Microbiol 2005 Mar 55(5):1315-24 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 5 Apr 2005

Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity.
Weber H, Polen T, …, Wendisch VF, Hengge R
J Bacteriol 2005 Mar 187(5):1591-603 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 4 Apr 2005

Differential ability of sigma(s) and sigma70 of Escherichia coli to utilize promoters containing half or full UP-element sites.
Typas A, Hengge R
Mol Microbiol 2005 Jan 55(1):250-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 11 Feb 2005

Redox-sensitive transcriptional control by a thiol/disulphide switch in the global regulator, Spx.
Nakano S, Erwin KN, Ralle M, Zuber P
Mol Microbiol 2005 Jan 55(2):498-510 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 11 Feb 2005

The TyrR regulon.
Pittard J, Camakaris H, Yang J
Mol Microbiol 2005 Jan 55(1):16-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 8 Feb 2005

T4 AsiA blocks DNA recognition by remodeling sigma70 region 4.
Lambert LJ, Wei Y, …, Demeler B, Werner MH
EMBO J 2004 Aug 4 23(15):2952-62 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 22 Nov 2004

Identification of the CRP regulon using in vitro and in vivo transcriptional profiling.
Zheng D, Constantinidou C, Hobman JL, Minchin SD
Nucleic Acids Res 2004 32(19):5874-93 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby / Regine Hengge
Evaluated 18 Nov 2004

Negative control of Listeria monocytogenes virulence genes by a diffusible autorepressor.
Ermolaeva S, Novella S, …, Scortti M, Vázquez-Boland JA
Mol Microbiol 2004 Apr 52(2):601-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 20 Apr 2004

Expression of the chitobiose operon of Escherichia coli is regulated by three transcription factors: NagC, ChbR and CAP.
Plumbridge J, Pellegrini O
Mol Microbiol 2004 Apr 52(2):437-49 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 20 Apr 2004

Interactions among CII protein, RNA polymerase and the lambda PRE promoter: contacts between RNA polymerase and the -35 region of PRE are identical in the presence and absence of CII protein.
Marr MT, Roberts JW, …, Klee M, Gussin GN
Nucleic Acids Res 2004 32(3):1083-90 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 4 Mar 2004

Multiple stress signal integration in the regulation of the complex sigma S-dependent csiD-ygaF-gabDTP operon in Escherichia coli.
Metzner M, Germer J, Hengge R
Mol Microbiol 2004 Feb 51(3):799-811 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 24 Feb 2004

Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression.
Beloin C, Valle J, …, Arbeille B, Ghigo JM
Mol Microbiol 2004 Feb 51(3):659-74 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 24 Feb 2004

Thermoregulation of the Escherichia coli O157:H7 pO157 ecf operon and lipid A myristoyl transferase activity involves intrinsically curved DNA.
Yoon JW, Minnich SA, …, Paszczynski A, Hovde CJ
Mol Microbiol 2004 Jan 51(2):419-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 24 Feb 2004

Nucleoid restructuring in stationary-state bacteria.
Frenkiel-Krispin D, Ben-Avraham I, …, Wolf SG, Minsky A
Mol Microbiol 2004 Jan 51(2):395-405 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Busby
Evaluated 24 Feb 2004

Evidence that acetyl phosphate functions as a global signal during biofilm development.
Wolfe AJ, Chang DE, …, Larkin JC, Conway T
Mol Microbiol 2003 May 48(4):977-88 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 21 Jul 2003

An intersubunit contact stimulating transcription initiation by E coli RNA polymerase: interaction of the alpha C-terminal domain and sigma region 4.
Ross W, Schneider DA, …, Mertens A, Gourse RL
Genes Dev 2003 May 15 17(10):1293-307 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 21 Jul 2003

Unified two-metal mechanism of RNA synthesis and degradation by RNA polymerase.
Sosunov V, Sosunova E, …, Nikiforov V, Goldfarb A
EMBO J 2003 May 1 22(9):2234-44 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 21 Jul 2003

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading.
Skordalakes E, Berger JM
Cell 2003 Jul 11 114(1):135-46 [abstract on PubMed] [related articles] [order article]
Selected by | Russell DiGate / Stephen Busby / Edward Egelman
Evaluated 21 Jul 2003

A regulatory protein that interferes with activator-stimulated transcription in bacteria.
Nakano S, Nakano MM, …, Leelakriangsak M, Zuber P
Proc Natl Acad Sci U S A 2003 Apr 1 100(7):4233-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tina Henkin / Victor DiRita / Stephen Busby
Evaluated 21 Jul 2003

The modular structure of Escherichia coli threonyl-tRNA synthetase as both an enzyme and a regulator of gene expression.
Caillet J, Nogueira T, …, Romby P, Springer M
Mol Microbiol 2003 Feb 47(4):961-74 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 11 Feb 2003

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine.
Starai VJ, Celic I, …, Boeke JD, Escalante-Semerena JC
Science 2002 Dec 20 298(5602):2390-2 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Robert Dutnall / Tina Henkin / Stephen Busby / Stephen Jackson
Evaluated 5 Feb 2003

The TRTGn motif stabilizes the transcription initiation open complex.
Voskuil MI, Chambliss GH
J Mol Biol 2002 Sep 20 322(3):521-32 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 4 Feb 2003

Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica.
Eriksson S, Lucchini S, …, Rhen M, Hinton JC
Mol Microbiol 2003 Jan 47(1):103-18 [abstract on PubMed] [related articles] [order article]
Selected by | Sergio Grinstein / Timo Korhonen / Stephen Busby / Julian Parkhill
Evaluated 4 Feb 2003

Genome-wide analysis of deoxyadenosine methyltransferase-mediated control of gene expression in Escherichia coli.
Oshima T, Wada C, …, Hiraga S, Mori H
Mol Microbiol 2002 Aug 45(3):673-95 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 27 Nov 2002

Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli.
Kawano M, Oshima T, Kasai H, Mori H
Mol Microbiol 2002 Jul 45(2):333-49 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 27 Nov 2002

Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12.
Oshima T, Aiba H, …, Mori H, Mizuno T
Mol Microbiol 2002 Oct 46(1):281-91 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 27 Nov 2002

Regulation and mode of action of the second small RNA activator of RpoS translation, RprA.
Majdalani N, Hernandez D, Gottesman S
Mol Microbiol 2002 Nov 46(3):813-26 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 27 Nov 2002

Structural basis of transcription activation: the CAP-alpha CTD-DNA complex.
Benoff B, Yang H, …, Berman HM, Ebright RH
Science 2002 Aug 30 297(5586):1562-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby / Peter Qin / Richard Gourse
Evaluated 9 Sep 2002

Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
Schumacher MA, Pearson RF, …, Valentin-Hansen P, Brennan RG
EMBO J 2002 Jul 1 21(13):3546-56 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Holbrook / Stephen Busby
Evaluated 1 Aug 2002

Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon.
Møller T, Franch T, …, Gerdes K, Valentin-Hansen P
Genes Dev 2002 Jul 1 16(13):1696-706 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby / Gisela Storz
Evaluated 31 Jul 2002

Genomics of the marA/soxS/rob regulon of Escherichia coli: identification of directly activated promoters by application of molecular genetics and informatics to microarray data.
Martin RG, Rosner JL
Mol Microbiol 2002 Jun 44(6):1611-24 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 30 Jul 2002

Complex formation between activator and RNA polymerase as the basis for transcriptional activation by MarA and SoxS in Escherichia coli.
Martin RG, Gillette WK, Martin NI, Rosner JL
Mol Microbiol 2002 Jan 43(2):355-70 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 12 Feb 2002

Solution structure and stability of the anti-sigma factor AsiA: implications for novel functions.
Urbauer JL, Simeonov MF, …, Gilmore JM, Brody EN
Proc Natl Acad Sci U S A 2002 Feb 19 99(4):1831-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Busby
Evaluated 11 Feb 2002

Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon.
Paget MS, Molle V, …, Aharonowitz Y, Buttner MJ
Mol Microbiol 2001 Nov 42(4):1007-20 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen Busby
Evaluated 20 Dec 2001

Promoter recognition and discrimination by EsigmaS RNA polymerase.
Gaal T, Ross W, …, Burgess RR, Gourse RL
Mol Microbiol 2001 Nov 42(4):939-54 [abstract on PubMed] [related articles] [order article]