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 | Bino John Department of Computational Biology, University of Pittsburgh School of Medicine & Cancer Institute, United States of America | | | Faculty Member: Genomics & Genetics > Bioinformatics [ since 25 June 2008 ] |
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Bino John sponsors free access to F1000 for Indian Institute of Technology. Supporting F1000's initiative to make itself available to scientists in all countries, including free access to developing countries (more details). | Biography
The broad objective of our research is to help cure human diseases by developing bioinformatics/computational and experimental methods to study gene functions. Recent studies link non-protein-coding RNAs to cancer and other diseases. Noncoding RNAs such as microRNAs are thought to post-transcriptionally regulate a large number of human genes. The research on non-coding RNAs is likely to provide new diagnostic and prognostic markers and eventually therapeutic targets for the treatment of human diseases. We also aim to develop methods to aid computer aided drug design efforts. Our research strategy is to apply bioinformatics/computational methods to formulate reasonable hypotheses about interesting biological problems and subsequently conduct experiments to test them. Current projects in our laboratory include but are not limited to:
1. Discovering new microRNAs
2. Identifying functions of specific disease (eg, viruses and cancer) associated microRNAs
3. Identifying novel gene regulatory networks in cancer and other diseases.
4. Developing new methods to determine protein/rna structure
Bino John, PhD, Asst. Professor
University of Pittsburgh School of Medicine & Cancer Institute
3080 Biomedical Science Tower 3
3501 Fifth Avenue
Pittsburgh, PA 15213,USA
Phone:(412) 648-8607
Email:
| Home page
http://www.johnlab.org |
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