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Carien Niessen
Center for Molecular Medicine, University of Cologne, Cologne, Germany

Faculty Member: Cell Biology > Cell Adhesion [ since 4 July 2001 ]
[ Evaluations ]
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Evaluations

The PDZ protein canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors.
Speicher S, Fischer A, Knoblich J, Carmena A
Curr Biol 2008 Jun 3 18(11):831-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carien Niessen
Evaluated 12 Jun 2008

A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity.
Nejsum LN, Nelson WJ
J Cell Biol 2007 Jul 16 178(2):323-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kenneth Yamada / Carien Niessen
Evaluated 22 Oct 2007

ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.
Umeda K, Ikenouchi J, …, Furuse M, Tsukita S
Cell 2006 Aug 25 126(4):741-54 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Fanning / Carien Niessen / Jeff Hardin
Evaluated 23 Mar 2007

PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.
Martin-Belmonte F, Gassama A, …, Gerke V, Mostov K
Cell 2007 Jan 26 128(2):383-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michel Labouesse / Salim Abdelilah-Seyfried / Valeri Vasioukhin / Carien Niessen / Andrew Chisholm
Evaluated 23 Mar 2007

PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.
Hirose T, Karasawa M, …, Ohno S, Noda T
Development 2006 Apr 133(7):1389-98 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Helen Gruber / Carien Niessen
Evaluated 24 Oct 2006

Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.
Drees F, Pokutta S, …, Nelson WJ, Weis WI
Cell 2005 Dec 2 123(5):903-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rong Li / Kenneth Yamada / Mariann Bienz / Frans Van Roy / William A Muller / Michel Labouesse / Marie-France Carlier / Kathleen J. Green / Carien Niessen
Evaluated 3 May 2006

Deconstructing the cadherin-catenin-actin complex.
Yamada S, Pokutta S, …, Weis WI, Nelson WJ
Cell 2005 Dec 2 123(5):889-901 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rong Li / Kenneth Yamada / Mariann Bienz / Frans Van Roy / William A Muller / Michel Labouesse / Thomas Lecuit / Kathleen J. Green / Carien Niessen / Jeff Hardin
Evaluated 6 Mar 2006

ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.
Maretzky T, Reiss K, …, Hartmann D, Saftig P
Proc Natl Acad Sci U S A 2005 Jun 28 102(26):9182-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kathleen J. Green / Carien Niessen
Evaluated 23 Nov 2005

Asymmetric cell divisions promote stratification and differentiation of mammalian skin.
Lechler T, Fuchs E
Nature 2005 Sep 8 437(7056):275-80 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Bilder / Sander van den Heuvel / Kenneth Zaret / Carien Niessen
Evaluated 23 Nov 2005

Regulatory mechanisms required for DE-cadherin function in cell migration and other types of adhesion.
Pacquelet A, Rørth P
J Cell Biol 2005 Aug 29 170(5):803-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carien Niessen
Evaluated 23 Nov 2005

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.
Chen X, Macara IG
Nat Cell Biol 2005 Mar 7(3):262-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin A. Schwartz / Alan Fanning / Carien Niessen
Evaluated 27 Jul 2005

High-throughput mapping of a dynamic signaling network in mammalian cells.
Barrios-Rodiles M, Brown KR, …, Jurisica I, Wrana JL
Science 2005 Mar 11 307(5715):1621-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan Chernoff / Carien Niessen / Richard Willson
Evaluated 18 Mar 2005

Antero-posterior tissue polarity links mesoderm convergent extension to axial patterning.
Ninomiya H, Elinson RP, Winklbauer R
Nature 2004 Jul 15 430(6997):364-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lilianna Solnica-Krezel / Herbert Steinbeisser / Carien Niessen
Evaluated 18 Mar 2005

Surface mechanics mediate pattern formation in the developing retina.
Hayashi T, Carthew RW
Nature 2004 Oct 7 431(7009):647-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Deborah Leckband / Talila Volk / Marta Llimargas / Buzz Baum / Jennifer Fletcher / Jeffrey Axelrod / Carien Niessen / Ross Cagan / David Bilder
Evaluated 13 Jan 2005

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck FH, Schwarz-Romond T, …, Hammerschmidt M, Birchmeier W
Genes Dev 2004 Sep 15 18(18):2225-30 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gregory Dressler / Valeri Vasioukhin / David Kimelman / Carien Niessen / Mariann Bienz
Evaluated 14 Oct 2004

Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation.
Bertet C, Sulak L, Lecuit T
Nature 2004 Jun 10 429(6992):667-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ben Zion Shilo / Michel Labouesse / Jeffrey Axelrod / Maria Leptin / Carien Niessen / Vivian Tang / Alfonso Martinez Arias
Evaluated 16 Jul 2004

Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.
Nastasi T, Bongiovanni A, …, Harris AJ, D'Azzo A
Dev Cell 2004 Feb 6(2):269-82 [abstract on PubMed] [related articles] [order article]
Selected by | Carien Niessen
Evaluated 7 Apr 2004

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.
Marambaud P, Wen PH, …, Siman R, Robakis NK
Cell 2003 Sep 5 114(5):635-45 [abstract on PubMed] [related articles] [order article]
Selected by | Mark Bothwell / Vance Lemmon / Anthony Means / Valeri Vasioukhin / Carien Niessen
Evaluated 9 Dec 2003

Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact.
Zhang F, Tom CC, …, Wei Y, Chapman HA
J Cell Biol 2003 Oct 13 163(1):177-88 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Valeri Vasioukhin / Carien Niessen / M. Sharon Stack
Evaluated 9 Dec 2003

Untangling desmosomal knots with electron tomography.
He W, Cowin P, Stokes DL
Science 2003 Oct 3 302(5642):109-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang / Tony Crowther / Carien Niessen
Evaluated 9 Dec 2003

Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho.
Martinez MC, Ochiishi T, Majewski M, Kosik KS
J Cell Biol 2003 Jul 7 162(1):99-111 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carien Niessen
Evaluated 20 Aug 2003

Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component.
Myster SH, Cavallo R, …, Fox DT, Peifer M
J Cell Biol 2003 Feb 3 160(3):433-49 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Albert Reynolds / Kathleen J. Green / Carien Niessen
Evaluated 29 May 2003

Binding site for p120/delta-catenin is not required for Drosophila E-cadherin function in vivo.
Pacquelet A, Lin L, Rorth P
J Cell Biol 2003 Feb 3 160(3):313-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carien Niessen
Evaluated 28 May 2003

Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength.
Huen AC, Park JK, …, Gumbiner BM, Green KJ
J Cell Biol 2002 Dec 23 159(6):1005-17 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vania Braga / Carien Niessen
Evaluated 26 Mar 2003

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.
Batlle E, Henderson JT, …, Pawson T, Clevers H
Cell 2002 Oct 18 111(2):251-63 [abstract on PubMed] [related articles] [order article]
Selected by | Mariann Bienz / Fiona Watt / Carien Niessen
Evaluated 3 Jan 2003

Myosin VI is required for E-cadherin-mediated border cell migration.
Geisbrecht ER, Montell DJ
Nat Cell Biol 2002 Aug 4(8):616-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Gillespie / Kathleen J. Green / Jean Schwarzbauer / John Hammer / Carien Niessen
Evaluated 2 Jan 2003

Invasive cell migration is initiated by guided growth of long cellular extensions.
Fulga TA, Rørth P
Nat Cell Biol 2002 Sep 4(9):715-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ben Zion Shilo / Marta Llimargas / Alain Ghysen / Carien Niessen
Evaluated 27 Nov 2002

SynCAM, a synaptic adhesion molecule that drives synapse assembly.
Biederer T, Sara Y, …, Kavalali ET, Südhof TC
Science 2002 Aug 30 297(5586):1525-31 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Valeri Vasioukhin / Genevieve Rougon / Oliver Hobert / Morgan Sheng / Carien Niessen / Elior Peles / W. Martin Usrey / Alain Prochiantz
Evaluated 25 Sep 2002

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
Malliri A, van der Kammen RA, …, Michiels F, Collard JG
Nature 2002 Jun 20 417(6891):867-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Channing Der / Anne Ridley / Carien Niessen
Evaluated 30 Aug 2002

Dynamics of ligand-induced, Rac1-dependent anchoring of cadherins to the actin cytoskeleton.
Lambert M, Choquet D, Mège RM
J Cell Biol 2002 Apr 29 157(3):469-79 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Alan Rick Horwitz / Vania Braga / Yoshimi Takai / Carien Niessen
Evaluated 25 Jul 2002

Germline stem cells anchored by adherens junctions in the Drosophila ovary niches.
Song X, Zhu CH, Doan C, Xie T
Science 2002 Jun 7 296(5574):1855-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Norbert Perrimon / Marta Llimargas / Carien Niessen
Evaluated 3 Jul 2002

Rac function and regulation during Drosophila development.
Hakeda-Suzuki S, Ng J, …, Luo L, Dickson BJ
Nature 2002 Mar 28 416(6879):438-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marta Llimargas / Siegfried Roth / Ruediger Klein / Carien Niessen
Evaluated 13 May 2002

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.
Marambaud P, Shioi J, …, Wisniewski T, Robakis NK
EMBO J 2002 Apr 15 21(8):1948-56 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carien Niessen / Kathleen J. Green
Evaluated 8 May 2002

Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin.
Vasioukhin V, Bauer C, …, Wise B, Fuchs E
Cell 2001 Feb 23 104(4):605-17 [abstract on PubMed] [related articles] [order article]
Selected by | Carien Niessen
Evaluated 28 Feb 2002

Rap1 GTPase regulation of adherens junction positioning and cell adhesion.
Knox AL, Brown NH
Science 2002 Feb 15 295(5558):1285-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gregory Dressler / Carien Niessen / Yoshimi Takai / Maria Leptin
Evaluated 28 Feb 2002

Crystal structure of Arp2/3 complex.
Robinson RC, Turbedsky K, …, Choe S, Pollard TD
Science 2001 Nov 23 294(5547):1679-84 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Marie-France Carlier / Elena Conti / Tony Crowther / Carien Niessen / David Lambright
Evaluated 2 Jan 2002

The Drosophila AP axis is polarised by the cadherin-mediated positioning of the oocyte.
González-Reyes A, St Johnston D
Development 1998 Sep 125(18):3635-44 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carien Niessen
Evaluated 7 Nov 2001

Drosophila oocyte localization is mediated by differential cadherin-based adhesion.
Godt D, Tepass U
Nature 1998 Sep 24 395(6700):387-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carien Niessen
Evaluated 25 Oct 2001

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