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Anna Huttenlocher
Departments of Pharmacology and Pediatrics, University of Wisconsin-Madison, Madison, United States of America

Faculty Member: Cell Biology > Cell Adhesion [ since 4 July 2001 ]
[ Evaluations ]
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Evaluations

PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils.
Heit B, Robbins SM, …, Jirik FR, Kubes P
Nat Immunol 2008 Jul 9(7):743-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marcus Thelen / Anna Huttenlocher / Steve Ward
Evaluated 24 Jun 2008

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility.
Lim Y, Lim ST, …, Waterman-Storer C, Schlaepfer DD
J Cell Biol 2008 Jan 14 180(1):187-203 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Huttenlocher
Evaluated 22 Jan 2008

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells.
Gaggioli C, Hooper S, …, Harrington K, Sahai E
Nat Cell Biol 2007 Dec 9(12):1392-400 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin A. Schwartz / Filippo Giancotti / Carol Otey / Frank de Gruijl / C. Michael DiPersio / Anna Huttenlocher / Kathleen J. Green
Evaluated 15 Jan 2008

Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling.
Keizer-Gunnink I, Kortholt A, Van Haastert PJ
J Cell Biol 2007 May 21 177(4):579-85 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher
Evaluated 25 May 2007

Reversal of the TCR stop signal by CTLA-4.
Schneider H, Downey J, …, Garside P, Rudd CE
Science 2006 Sep 29 313(5795):1972-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christian Engwerda / Anna Huttenlocher
Evaluated 18 Oct 2006

Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster.
Wood W, Faria C, Jacinto A
J Cell Biol 2006 May 8 173(3):405-16 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher
Evaluated 10 May 2006

Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site.
Féral CC, Rose DM, …, Kaushansky K, Ginsberg MH
J Clin Invest 2006 Mar 116(3):715-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher / Giorgio Berton / Clifford Lowell
Evaluated 1 Mar 2006

Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin.
Ulrich F, Krieg M, …, Puech PH, Heisenberg CP
Dev Cell 2005 Oct 9(4):555-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Adam Linstedt / Jim Smith / Erez Raz / Anna Huttenlocher / Lilianna Solnica-Krezel
Evaluated 26 Oct 2005

Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity.
Bano D, Young KW, …, Carafoli E, Nicotera P
Cell 2005 Jan 28 120(2):275-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Sapolsky / Anna Huttenlocher / Christoph Borner
Evaluated 6 Apr 2005

RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers.
de Hoog CL, Foster LJ, Mann M
Cell 2004 May 28 117(5):649-62 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Ekblom / Francisco Sanchez-Madrid / Martin Humphries / Michael Gold / Anna Huttenlocher
Evaluated 1 Nov 2004

Activation of endogenous Cdc42 visualized in living cells.
Nalbant P, Hodgson L, …, Toutchkine A, Hahn KM
Science 2004 Sep 10 305(5690):1615-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Beverly Wendland / Anna Huttenlocher / Martin Humphries / Wen-hong Li
Evaluated 22 Sep 2004

Fibronectin regulates epithelial organization during myocardial migration in zebrafish.
Trinh LA, Stainier DY
Dev Cell 2004 Mar 6(3):371-82 [abstract on PubMed] [related articles] [order article]
Selected by | Anna Huttenlocher
Evaluated 19 Jul 2004

Regulation of cell migration and survival by focal adhesion targeting of Lasp-1.
Lin YH, Park ZY, …, Yates JR, Klemke RL
J Cell Biol 2004 May 10 165(3):421-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher
Evaluated 16 Jul 2004

Integrins regulate Rac targeting by internalization of membrane domains.
del Pozo MA, Alderson NB, …, Anderson RG, Schwartz MA
Science 2004 Feb 6 303(5659):839-42 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Valeri Vasioukhin / Robert Parton / Kermit Carraway / Anna Huttenlocher / Martin Humphries / Charles Streuli
Evaluated 24 Feb 2004

alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion.
Chattopadhyay N, Wang Z, …, Brady-Kalnay SM, Kreidberg JA
J Cell Biol 2003 Dec 22 163(6):1351-62 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dietmar Vestweber / Anna Huttenlocher
Evaluated 6 Feb 2004

A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src.
Carragher NO, Westhoff MA, …, Schaller MD, Frame MC
Curr Biol 2003 Aug 19 13(16):1442-50 [abstract on PubMed] [related articles] [order article]
Selected by | Anna Huttenlocher / Alan Rick Horwitz / Jean Schwarzbauer
Evaluated 2 Sep 2003

Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin.
Wong AS, Gumbiner BM
J Cell Biol 2003 Jun 23 161(6):1191-203 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vania Braga / Anna Huttenlocher / Valeri Vasioukhin
Evaluated 28 Jul 2003

Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase.
Wedlich-Soldner R, Altschuler S, Wu L, Li R
Science 2003 Feb 21 299(5610):1231-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Michael Dustin / Anna Huttenlocher / R. Dyche Mullins
Evaluated 9 Apr 2003

Wound healing recapitulates morphogenesis in Drosophila embryos.
Wood W, Jacinto A, …, Wilson C, Martin P
Nat Cell Biol 2002 Nov 4(11):907-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Huttenlocher / Anne Ridley / Daniel Kiehart
Evaluated 7 Nov 2002

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.
Iijima M, Devreotes P
Cell 2002 May 31 109(5):599-610 [abstract on PubMed] [related articles] [order article]
Selected by | Silvia Arber / Silvio Gutkind / Steve Ward / Bruce Conklin / Phillip Hawkins / Jeffrey Axelrod / Henry R. Bourne / David Lambright / Anna Huttenlocher / Andreas Wodarz / Richard Gomer / Gerald Weeks
Evaluated 25 Jul 2002

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton.
Krendel M, Zenke FT, Bokoch GM
Nat Cell Biol 2002 Apr 4(4):294-301 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Bement / Anna Huttenlocher
Evaluated 13 May 2002

Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold.
Cho SY, Klemke RL
J Cell Biol 2002 Feb 18 156(4):725-36 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher / Jean Schwarzbauer
Evaluated 8 Mar 2002

The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling.
Hagel M, George EL, …, Imamoto A, Thomas SM
Mol Cell Biol 2002 Feb 22(3):901-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher
Evaluated 4 Feb 2002

Taking cell-matrix adhesions to the third dimension.
Cukierman E, Pankov R, Stevens DR, Yamada KM
Science 2001 Nov 23 294(5547):1708-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Martin Humphries / Anna Huttenlocher / Dafna Bar-Sagi / Charles Streuli
Evaluated 7 Dec 2001

Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo.
Xu J, Rodriguez D, …, Brooks PC, Yuen SM
J Cell Biol 2001 Sep 3 154(5):1069-79 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher
Evaluated 5 Oct 2001

Contact interactions between epitheliocytes and fibroblasts: formation of heterotypic cadherin-containing adhesion sites is accompanied by local cytoskeletal reorganization.
Omelchenko T, Fetisova E, …, Vasiliev JM, Gelfand IM
Proc Natl Acad Sci U S A 2001 Jul 17 98(15):8632-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anna Huttenlocher
Evaluated 5 Oct 2001

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