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William Welch
Division of Nephrology and Hypertension, Georgetown University, Washington, United States of America

Faculty Member: Physiology > Renal, Fluid & Electrolyte Physiology [ since 24 March 2005 ]
[ Evaluations ]
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Evaluations

Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone.
Pochynyuk O, Bugaj V, …, Vallon V, Stockand JD
J Biol Chem 2008 Nov 3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 17 Nov 2008

Suppression of renin-angiotensin gene expression in the kidney by paricalcitol.
Freundlich M, Quiroz Y, …, Li YC, Rodriguez-Iturbe B
Kidney Int 2008 Aug 27 [abstract on PubMed] [related articles] [full text]
Selected by | William Welch
Evaluated 10 Oct 2008

Effects of dietary salt on renal Na+ transporters' subcellular distribution, abundance, and phosphorylation status.
Yang LE, Sandberg MB, …, Pihakaski-Maunsbach K, McDonough AA
Am J Physiol Renal Physiol 2008 Jul 23 [abstract on PubMed] [related articles] [full text]
Selected by | William Welch
Evaluated 18 Aug 2008

Characterization of the Sodium/Hydrogen Exchanger NHA2.
Fuster DG, Zhang J, …, Andersson S, Moe OW
J Am Soc Nephrol 2008 May 28 [abstract on PubMed] [related articles] [full text]
Selected by | William Welch
Evaluated 25 Jul 2008

Effect of chronic inhibition of converting enzyme on proximal tubule acidification.
Diaz-Sylvester PL, Fiori MC, …, Lopardo ML, Amorena CE
Am J Physiol Regul Integr Comp Physiol 2008 Apr 9 [abstract on PubMed] [related articles]
Selected by | William Welch
Evaluated 20 May 2008

Collecting Duct Renin is Upregulated in Both Kidneys of 2-Kidney, 1-Clip Goldblatt Hypertensive Rats.
Prieto-Carrasquero MC, Botros FT, …, Casarini DE, Navar LG
Hypertension 2008 Apr 21 [abstract on PubMed] [related articles] [full text]
Selected by | William Welch
Evaluated 19 May 2008

Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension.
Yogi A, Mercure C, …, Reudelhuber T, Touyz RM
Hypertension 2008 Feb 51(2):500-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 13 Mar 2008

Positron-emission tomography imaging of the angiotensin II subtype 1 receptor in swine renal artery stenosis.
Xia J, Seckin E, …, Lerman LO, Szabo Z
Hypertension 2008 Feb 51(2):466-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 6 Feb 2008

Dipeptidyl Peptidase IV Inhibition Downregulates Na+-H+ Exchanger NHE3 in Rat Renal Proximal Tubule.
Girardi AC, Fukuda LE, …, Malnic G, Reboucas NA
Am J Physiol Renal Physiol 2007 Dec 12 [abstract on PubMed] [related articles] [full text]
Selected by | William Welch
Evaluated 21 Dec 2007

Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress.
Nagase M, Matsui H, …, Gotoda T, Fujita T
Hypertension 2007 Nov 50(5):877-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 23 Oct 2007

Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress.
Datla SR, Dusting GJ, …, Croft KD, Jiang F
Hypertension 2007 Oct 50(4):636-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 21 Aug 2007

Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats.
Krebs C, Hamming I, …, Nguyen G, Wenzel U
Kidney Int 2007 Sep 72(6):725-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 25 Jul 2007

Inhibitor of growth 4 (ING4) is up-regulated by a low K intake and suppresses renal outer medullary K channels (ROMK) by MAPK stimulation.
Zhang X, Lin DH, …, Han ZG, Wang WH
Proc Natl Acad Sci U S A 2007 May 29 104(22):9517-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 8 Jun 2007

Selective knockdown of AT1 receptors by RNA interference inhibits Val5-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells.
Li XC, Zhuo JL
Am J Physiol Cell Physiol 2007 Jul 293(1):C367-78 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 20 Apr 2007

Effect of the angiotensinogen genotype on experimental hypertension in mice.
Handtrack C, Cordasic N, …, Veelken R, Hilgers KF
J Mol Med 2007 Apr 85(4):343-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 21 Mar 2007

Amelioration of progressive renal injury by genetic manipulation of Klotho gene.
Haruna Y, Kashihara N, …, Xie P, Kanwar YS
Proc Natl Acad Sci U S A 2007 Feb 13 104(7):2331-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 20 Feb 2007


Prenatal programming of rat proximal tubule Na+/H+ exchanger by dexamethasone.
Dagan A, Gattineni J, Cook V, Baum M
Am J Physiol Regul Integr Comp Physiol 2007 Mar 292(3):R1230-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 24 Jan 2007

Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
Li H, Gao Y, …, Katovich MJ, Sumners C
Am J Physiol Heart Circ Physiol 2007 Feb 292(2):H727-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 12 Dec 2006

Overexpression of human WNK1 increases paracellular chloride permeability and phosphorylation of claudin-4 in MDCKII cells.
Ohta A, Yang SS, …, Sasaki S, Uchida S
Biochem Biophys Res Commun 2006 Oct 20 349(2):804-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 12 Dec 2006

Proximal tubule microvilli remodeling and albuminuria in the Ren2 transgenic rat.
Hayden MR, Chowdhury NA, …, Stump C, Sowers JR
Am J Physiol Renal Physiol 2007 Feb 292(2):F861-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 7 Nov 2006

Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats.
Sánchez-Lozada LG, Tapia E, …, Herrera-Acosta J, Franco M
Am J Physiol Renal Physiol 2007 Jan 292(1):F423-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 4 Oct 2006

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.
Nakagawa K, Holla VR, …, Waterman MR, Capdevila JH
J Clin Invest 2006 Jun 116(6):1696-702 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Aniko Naray-Fejes-Toth / William Welch
Evaluated 8 Aug 2006

Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice.
Dziarmaga A, Eccles M, Goodyer P
J Am Soc Nephrol 2006 Jun 17(6):1568-75 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 21 Jul 2006

Angiotensin II mediates downregulation of aquaporin water channels and key renal sodium transporters in response to urinary tract obstruction.
Jensen AM, Li C, …, Nielsen S, Frøkiaer J
Am J Physiol Renal Physiol 2006 Nov 291(5):F1021-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 28 Jun 2006

Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase.
Kim J, Kil IS, …, Bonventre JV, Park KM
J Biol Chem 2006 Jul 21 281(29):20349-56 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 25 May 2006

Transforming growth factor-beta 1 stimulates angiotensinogen gene expression in kidney proximal tubular cells.
Brezniceanu ML, Wei CC, …, Filep JG, Chan JS
Kidney Int 2006 Jun 69(11):1977-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 20 Apr 2006

Diabetic endothelin B receptor-deficient rats develop severe hypertension and progressive renal failure.
Pfab T, Thöne-Reineke C, …, Yanagisawa M, Hocher B
J Am Soc Nephrol 2006 Apr 17(4):1082-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 9 Mar 2006

Theophylline improves early allograft function in rat kidney transplantation.
Grenz A, Baier D, …, Fandrich F, Osswald H
J Pharmacol Exp Ther 2006 May 317(2):473-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 3 Feb 2006

The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice.
Xu S, Jiang B, …, Zuccollo A, Cohen RA
Diabetes 2006 Jan 55(1):110-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 12 Jan 2006

Renal hyperfiltration in type 2 diabetes: effect of age-related decline in glomerular filtration rate.
Premaratne E, Macisaac RJ, …, Smith T, Jerums G
Diabetologia 2005 Dec 48(12):2486-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 1 Dec 2005

Secreted frizzled-related protein-4 reduces sodium-phosphate co-transporter abundance and activity in proximal tubule cells.
Berndt TJ, Bielesz B, …, Murer H, Kumar R
Pflugers Arch 2006 Jan 451(4):579-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 29 Sep 2005

Serum superoxide dismutase 3 (extracellular superoxide dismutase) activity is a sensitive indicator of Cu status in rats.
Johnson WT, Johnson LA, Lukaski HC
J Nutr Biochem 2005 Nov 16(11):682-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 9 Sep 2005

Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.
Sohara E, Rai T, …, Sasaki S, Uchida S
Am J Physiol Renal Physiol 2005 Dec 289(6):F1195-200 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 22 Jul 2005

Resistance to oxidative stress by chronic infusion of angiotensin II in mouse kidney is not mediated by the AT2 receptor.
Wesseling S, Ishola DA, …, Koomans HA, Braam B
Am J Physiol Renal Physiol 2005 Jun 288(6):F1191-200 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 3 Jun 2005

NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.
Satoh M, Fujimoto S, …, Makino H, Kashihara N
Am J Physiol Renal Physiol 2005 Jun 288(6):F1144-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Welch
Evaluated 27 May 2005

Increased glomerular and extracellular malondialdehyde levels in patients and rats with focal segmental glomerulosclerosis.
Kuo HT, Kuo MC, …, Guh JY, Chen HC
Eur J Clin Invest 2005 Apr 35(4):245-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Welch
Evaluated 26 Apr 2005

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