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Jia-huai Wang
Departments of Pediatrics, Biological Chemistry and Molecular Pharmacology,, Dana-Farber Cancer Center, United States of America

Faculty Member: Structural Biology > Cell Signalling & Trafficking Structures [ since 9 May 2002 ]
[ Evaluations ]
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Evaluations

Identification of specific histidines as pH sensors in flavivirus membrane fusion.
Fritz R, Stiasny K, Heinz FX
J Cell Biol 2008 Oct 20 183(2):353-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 28 Oct 2008

Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes.
Armstrong KM, Piepenbrink KH, Baker BM
Biochem J 2008 Oct 15 415(2):183-96 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 30 Sep 2008

Rapid leukocyte migration by integrin-independent flowing and squeezing.
Lämmermann T, Bader BL, …, Fässler R, Sixt M
Nature 2008 May 1 453(7191):51-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Friedemann Kiefer / Kenneth Yamada / Jens V. Stein / Vivian Tang / Carol Otey with Taofei Yin / Jia-huai Wang / Thomas Egelhoff
Evaluated 9 Jul 2008


Synthetic antibodies for specific recognition and crystallization of structured RNA.
Ye JD, Tereshko V, …, Kossiakoff AA, Piccirilli JA
Proc Natl Acad Sci U S A 2008 Jan 8 105(1):82-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Batey / Richard Willson / Jim Maher / Jia-huai Wang
Evaluated 11 Apr 2008

HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Arthos J, Cicala C, …, Goode DJ, Fauci AS
Nat Immunol 2008 Mar 9(3):301-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang / Claire Chougnet
Evaluated 21 Feb 2008


Sequence alignment for molecular replacement.
Barton GJ
Acta Crystallogr D Biol Crystallogr 2008 Jan 64(Pt 1):25-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 6 Feb 2008

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor.
Borg NA, Wun KS, …, McCluskey J, Rossjohn J
Nature 2007 Jul 5 448(7149):44-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Branch Moody / Edward Collins / Toshinori Nakayama / Jia-huai Wang / Moriya Tsuji
Evaluated 30 Jul 2007

Five retracted structure reports: inverted or incorrect?
Matthews BW
Protein Sci 2007 Jun 16(6):1013-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 13 Jul 2007

The highly cooperative folding of small naturally occurring proteins is likely the result of natural selection.
Watters AL, Deka P, …, Sosnick T, Baker D
Cell 2007 Feb 9 128(3):613-24 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang / Reinhard Sterner / Sophie Jackson
Evaluated 5 Mar 2007

Crystal structure of a rhomboid family intramembrane protease.
Wang Y, Zhang Y, Ha Y
Nature 2006 Nov 9 444(7116):179-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Koreaki Ito / Peter Artymiuk / Jia-huai Wang / Stephan Nussberger
Evaluated 15 Dec 2006

Structure of the insulin receptor ectodomain reveals a folded-over conformation.
McKern NM, Lawrence MC, …, Epa VC, Ward CW
Nature 2006 Sep 14 443(7108):218-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stevan Hubbard / Jia-huai Wang
Evaluated 18 Oct 2006

Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-A resolution.
Min G, Wang H, Sun TT, Kong XP
J Cell Biol 2006 Jun 19 173(6):975-83 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang
Evaluated 22 Jun 2006

How TCRs bind MHCs, peptides, and coreceptors.
Rudolph MG, Stanfield RL, Wilson IA
Annu Rev Immunol 2006 24:419-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang / Jamie Rossjohn
Evaluated 3 Feb 2006

Subunit arrangement and function in NMDA receptors.
Furukawa H, Singh SK, Mancusso R, Gouaux E
Nature 2005-11-10 438(7065):185-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang / Stuart Cull-Candy
Evaluated 8 Dec 2005

Structure of SARS coronavirus spike receptor-binding domain complexed with receptor.
Li F, Li W, Farzan M, Harrison SC
Science 2005 Sep 16 309(5742):1864-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang
Evaluated 10 Oct 2005

A GLYmmer of insight into fibril formation.
Uversky VN
Structure 2005 Aug 13(8):1090-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 30 Aug 2005

The alpha helix dipole: screened out?
Sengupta D, Behera RN, Smith JC, Ullmann GM
Structure 2005 Jun 13(6):849-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rebecca Wade / Jia-huai Wang
Evaluated 27 Jun 2005

Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.
Adams EJ, Chien YH, Garcia KC
Science 2005 Apr 8 308(5719):227-31 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang / Peter Hudson
Evaluated 28 Apr 2005

Structure of an unliganded simian immunodeficiency virus gp120 core.
Chen B, Vogan EM, …, Wiley DC, Harrison SC
Nature 2005 Feb 24 433(7028):834-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 3 Mar 2005

Disulfide isomerization after membrane release of its SAR domain activates P1 lysozyme.
Xu M, Arulandu A, …, Sacchettini JC, Young R
Science 2005 Jan 7 307(5706):113-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang
Evaluated 31 Jan 2005

Structure of human follicle-stimulating hormone in complex with its receptor.
Fan QR, Hendrickson WA
Nature 2005 Jan 20 433(7023):269-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 26 Jan 2005

10 residue folded peptide designed by segment statistics.
Honda S, Yamasaki K, Sawada Y, Morii H
Structure 2004 Aug 12(8):1507-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 6 Sep 2004

Structural rearrangements in the membrane penetration protein of a non-enveloped virus.
Dormitzer PR, Nason EB, Prasad BV, Harrison SC
Nature 2004 Aug 26 430(7003):1053-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang
Evaluated 1 Sep 2004

Three-dimensional rearrangement of proteins in the tail of bacteriophage T4 on infection of its host.
Leiman PG, Chipman PR, …, Mesyanzhinov VV, Rossmann MG
Cell 2004 Aug 20 118(4):419-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 31 Aug 2004

Protein-protein interactions; coupling of structurally conserved residues and of hot spots across interfaces. Implications for docking.
Halperin I, Wolfson H, Nussinov R
Structure 2004 Jun 12(6):1027-38 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 5 Jul 2004

Crystal structure of spinach major light-harvesting complex at 2.72 A resolution.
Liu Z, Yan H, …, An X, Chang W
Nature 2004 Mar 18 428(6980):287-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang / Jose Carrascosa / Wolfgang Junge / Petra Fromme
Evaluated 19 Mar 2004

Structure of the dengue virus envelope protein after membrane fusion.
Modis Y, Ogata S, Clements D, Harrison SC
Nature 2004 Jan 22 427(6972):313-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Collinson / Jia-huai Wang / Bernard Moss
Evaluated 4 Feb 2004

X-ray structure of a protein-conducting channel.
Van den Berg B, Clemons WM, …, Harrison SC, Rapoport TA
Nature 2004 Jan 1 427(6969):36-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Koreaki Ito / Karin Romisch / Jia-huai Wang / Stephen White / Tracy Palmer / Davis Ng / Senyon Choe / Ada Yonath / Kiyoshi Nagai / Manfred Schliwa / Bernd Bukau / Douglas Freymann
Evaluated 8 Jan 2004

Is it jolly SAD?
Dodson E
Acta Crystallogr D Biol Crystallogr 2003 Nov 59(Pt 11):1958-65 [abstract on PubMed] [related articles] [order article]
Selected by | Jia-huai Wang
Evaluated 21 Nov 2003

Untangling desmosomal knots with electron tomography.
He W, Cowin P, Stokes DL
Science 2003 Oct 3 302(5642):109-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang / Tony Crowther / Carien Niessen
Evaluated 15 Oct 2003

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Calarese DA, Scanlan CN, …, Burton DR, Wilson IA
Science 2003 Jun 27 300(5628):2065-71 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Crowe / Jia-huai Wang / Christopher Garcia / Peter Hudson / Sachdev Sidhu
Evaluated 22 Jul 2003

Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc.
Herr AB, Ballister ER, Bjorkman PJ
Nature 2003 Jun 5 423(6940):614-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 1 Jul 2003

The Genome sequence of the SARS-associated coronavirus.
Marra MA, Jones SJ, …, Upton C, Roper RL
Science 2003 May 30 300(5624):1399-404 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang
Evaluated 10 Jun 2003

Characterization of a novel coronavirus associated with severe acute respiratory syndrome.
Rota PA, Oberste MS, …, Anderson LJ, Bellini WJ
Science 2003 May 30 300(5624):1394-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang
Evaluated 10 Jun 2003

The structural biology of type I viral membrane fusion.
Colman PM, Lawrence MC
Nat Rev Mol Cell Biol 2003 Apr 4(4):309-19 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 14 May 2003

Variation on an Src-like theme.
Harrison SC
Cell 2003 Mar 21 112(6):737-40 [abstract on PubMed] [related articles] [order article]
Selected by | Jia-huai Wang
Evaluated 1 Apr 2003

A novel protein fold and extreme domain swapping in the dimeric TorD chaperone from Shewanella massilia.
Tranier S, Iobbi-Nivol C, …, Méjean V, Samama JP
Structure 2003 Feb 11(2):165-74 [abstract on PubMed] [related articles] [order article]
Selected by | Jia-huai Wang / David Richardson
Evaluated 13 Feb 2003

Collagen-binding mode of vWF-A3 domain determined by a transferred cross-saturation experiment.
Nishida N, Sumikawa H, …, Suzuki E, Shimada I
Nat Struct Biol 2003 Jan 10(1):53-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mitsuhiko Ikura / Jia-huai Wang
Evaluated 13 Jan 2003

Neural and immunological synaptic relations.
Dustin ML, Colman DR
Science 2002 Oct 25 298(5594):785-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 6 Nov 2002

Sequence and structural differences between enzyme and nonenzyme homologs.
Todd AE, Orengo CA, Thornton JM
Structure 2002 Oct 10(10):1435-51 [abstract on PubMed] [related articles] [order article]
Selected by | Jia-huai Wang
Evaluated 5 Nov 2002

Structure of the extracellular region of HER3 reveals an interdomain tether.
Cho HS, Leahy DJ
Science 2002 Aug 23 297(5585):1330-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kristina Downing / Mario Amzel / Jia-huai Wang / Kermit Carraway
Evaluated 4 Sep 2002

C-cadherin ectodomain structure and implications for cell adhesion mechanisms.
Boggon TJ, Murray J, …, Gumbiner BM, Shapiro L
Science 2002 May 17 296(5571):1308-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Robert Liddington / Vance Lemmon / Carlos Ibanez / Charles Streuli / Jia-huai Wang / David Stokes
Evaluated 11 Jun 2002

Designing a 20-residue protein.
Neidigh JW, Fesinmeyer RM, Andersen NH
Nat Struct Biol 2002 Jun 9(6):425-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jia-huai Wang
Evaluated 7 Jun 2002

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism.
Locher KP, Lee AT, Rees DC
Science 2002 May 10 296(5570):1091-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jia-huai Wang / Christel Tampe / Stephan Wilkens / Gary Yellen / Catherine Drennan / Andreas Engel / Wil Konings
Evaluated 20 May 2002

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