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Russ Hille
Department of Biochemistry, University of California, Riverside, Riverside, United States of America

Faculty Member: Chemical Biology > Bioinorganic Chemistry [ since 20 November 2006 ]
[ Biography ] [ Homepage ] [ Evaluations ]
Biography

RESEARCH INTERESTS
Structure/function relationships in redox-active enzymes; Inorganic biochemistry, particularly involving molybdenum; Spectroscopy of redox-active proteins; Biological electron transfer

EXPERIENCE
Professor, Department of Molecular and Cellular Biochemistry (principal academic appointment); Professor, Department of Chemistry; Investigator, Dorothy Davis Heart/Lung Research Institute; The Ohio State Biochemistry Program; Biophysics Graduate Program; Integrated Biomedical Science Graduate Program; Medical Scientist Program

Honors and Awards
Phi Kappa Phi Honors Fraternity, Texas Tech University, Lubbock, TX, April 1974
Rice University Fellowship, Rice University, Houston, TX, Academic Year, 1974 - 1975
Michigan Society of Fellows, University of Michigan, Ann Arbor, MI, August 1978 - August 1981
Simson Faculty Research Award, College of Medicine, The Ohio State University, 1997
Humboldt Research Prize, Alexander von Humboldt Foundation, Germany, 2003-2004
Fellow of the American Association for the Advancement of Science, October, 2004
Wenner-Gren Visiting Professorship, University of Lund, Sweden, 2007

RECENT PROFESSIONAL SERVICE
Physical Biochemistry Study Section, National Institutes of Health; July 1996 ? June 2000
Editorial Board, The Journal of Biological Chemistry, July 1996 ? June 2001; July 2002 ? present
Co-organizer, Molybdenum Enzymes Meeting, University of Sussex, Brighton, UK (April 1997)
Co-organizer, Molybdenum/Tungsten Enzymes Gordon Conference, Plymouth, NH (July 1999)
Chair, Molybdenum and Tungsten Enzymes Nomenclature Committee (July 2001 ? July 2004)
International Scientific Advisory Committee, 14th and 15th International Symposia on Flavins and Flavoproteins (Tokyo, Japan; Jaca, Spain) April 2003 ? present
Chair, Computational Biophysics Study Section, National Institutes of Health ? November, 2005

Home page

http://medicine.osu.edu/mcbiochem/Faculty%20Pages/Hille.html

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Evaluations

A role for confined water in chaperonin function.
England JL, Lucent D, Pande VS
J Am Chem Soc 2008 Sep 10 130(36):11838-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Shea / Russ Hille
Evaluated 16 Sep 2008

The crystal structure of a mammalian fatty acid synthase.
Maier T, Leibundgut M, Ban N
Science 2008 Sep 5 321(5894):1315-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / David Cane / Senyon Choe
Evaluated 15 Sep 2008

Most efficient cocaine hydrolase designed by virtual screening of transition states.
Zheng F, Yang W, …, Woods JH, Zhan CG
J Am Chem Soc 2008 Sep 10 130(36):12148-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 15 Sep 2008

The crystal structure of [Fe]-hydrogenase reveals the geometry of the active site.
Shima S, Pilak O, …, Thauer RK, Ermler U
Science 2008 Jul 25 321(5888):572-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Maroney / Russ Hille / Andrea Mattevi
Evaluated 7 Aug 2008

Kemp elimination catalysts by computational enzyme design.
Röthlisberger D, Khersonsky O, …, Tawfik DS, Baker D
Nature 2008 May 8 453(7192):190-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barry Stoddard / Reinhard Sterner / Russ Hille / Andreas Marx / Alfred Wittinghofer / Gabriele Varani
Evaluated 15 May 2008

Life without RNase P.
Randau L, Schröder I, Söll D
Nature 2008 May 1 453(7191):120-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / Judy Wall / Peter Unrau
Evaluated 8 May 2008

Selenite Assimilation into Formate Dehydrogenase H Depends on Thioredoxin Reductase in Escherichia coli.
Takahata M, Tamura T, …, Esaki N, Inagaki K
J Biochem 2008 Apr 143(4):467-473 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 15 Apr 2008

Dithiomethylether as a ligand in the hydrogenase h-cluster.
Pandey AS, Harris TV, …, Peters JW, Szilagyi RK
J Am Chem Soc 2008 Apr 2 130(13):4533-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 31 Mar 2008

A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity.
Richardson AR, Libby SJ, Fang FC
Science 2008 Mar 21 319(5870):1672-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / David Woodley
Evaluated 31 Mar 2008

NADP regulates the yeast GAL induction system.
Kumar PR, Yu Y, …, Johnston SA, Joshua-Tor L
Science 2008 Feb 22 319(5866):1090-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jim Maher / Russ Hille / Ian Booth
Evaluated 13 Mar 2008

Carbon dioxide activation at the Ni,Fe-cluster of anaerobic carbon monoxide dehydrogenase.
Jeoung JH, Dobbek H
Science 2007 Nov 30 318(5855):1461-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 3 Jan 2008

Crystal structure of a catalytic intermediate of the maltose transporter.
Oldham ML, Khare D, …, Davidson AL, Chen J
Nature 2007 Nov 22 450(7169):515-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / Hendrik W. van Veen
Evaluated 29 Nov 2007

Mapping hydration dynamics around a protein surface.
Zhang L, Wang L, …, Okobiah O, Zhong D
Proc Natl Acad Sci U S A 2007 Nov 20 104(47):18461-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Russ Hille
Evaluated 29 Nov 2007

YfaE, a ferredoxin involved in diferric-tyrosyl radical maintenance in Escherichia coli ribonucleotide reductase.
Wu CH, Jiang W, Krebs C, Stubbe J
Biochemistry 2007 Oct 16 46(41):11577-88 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 25 Oct 2007

Cobalt stress in Escherichia coli. The effect on the iron-sulfur proteins.
Ranquet C, Ollagnier-de-Choudens S, …, Barras F, Fontecave M
J Biol Chem 2007 Oct 19 282(42):30442-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 25 Oct 2007

AurF from Streptomyces thioluteus and a possible new family of manganese/iron oxygenases.
Krebs C, Matthews ML, Jiang W, Bollinger JM
Biochemistry 2007 Sep 18 46(37):10413-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 17 Sep 2007

X-ray structure analysis of a metalloprotein with enhanced active-site resolution using in situ x-ray absorption near edge structure spectroscopy.
Arcovito A, Benfatto M, …, Vallone B, Della Longa S
Proc Natl Acad Sci U S A 2007 Apr 10 104(15):6211-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Russ Hille
Evaluated 17 Apr 2007

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.
Wiley SE, Murphy AN, …, van der Geer P, Dixon JE
Proc Natl Acad Sci U S A 2007 Mar 27 104(13):5318-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Russ Hille
Evaluated 5 Apr 2007

Ammonia production at the FeMo cofactor of nitrogenase: results from density functional theory.
Kästner J, Blöchl PE
J Am Chem Soc 2007 Mar 14 129(10):2998-3006 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 16 Mar 2007

Structure of an ABC transporter in complex with its binding protein.
Hollenstein K, Frei DC, Locher KP
Nature 2007 Mar 8 446(7132):213-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / Frederick Hughson / Stephan Wilkens
Evaluated 14 Mar 2007

Structure of the non-redox-active tungsten/[4Fe:4S] enzyme acetylene hydratase.
Seiffert GB, Ullmann GM, …, Kroneck PMH, Einsle O
Proc Natl Acad Sci U S A 2007 104:3073-3077 [full text]
Selected by | Russ Hille
Evaluated 5 Mar 2007

Assignment of individual metal redox states in a metalloprotein by crystallographic refinement at multiple X-ray wavelengths.
Einsle O, Andrade SL, …, Meyer J, Rees DC
J Am Chem Soc 2007 Feb 28 129(8):2210-1 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / James Penner-Hahn
Evaluated 27 Feb 2007

Chemical and spectroscopic evidence for an FeV-oxo complex.
Tiago de Oliveira F, Chanda A, …, Münck E, Collins TJ
Science 2007 Feb 9 315(5813):835-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille
Evaluated 13 Feb 2007

Quantitative dynamics and binding studies of the 20S proteasome by NMR.
Sprangers R, Kay LE
Nature 2007 Feb 8 445(7128):618-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / Xiayang Qiu / Antonio Rosato / Dorothee Kern / Gottfried Otting / Josep Rizo
Evaluated 13 Feb 2007

The cellular machinery of Ferroplasma acidiphilum is iron-protein-dominated.
Ferrer M, Golyshina OV, …, Golyshin PN, Timmis KN
Nature 2007 Jan 4 445(7123):91-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Russ Hille / Carlos Pedrós-Alió
Evaluated 23 Jan 2007

Counting low-copy number proteins in a single cell.
Huang B, Wu H, …, Kobilka BK, Zare RN
Science 2007 Jan 5 315(5808):81-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Sweedler / Russ Hille
Evaluated 22 Jan 2007

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA.
Walden WE, Selezneva AI, …, Theil EC, Volz K
Science 2006 Dec 22 314(5807):1903-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barry Stoddard / Walter Chazin / Russ Hille / Angela Wilks / Daniel Gallie
Evaluated 15 Jan 2007

Bis(dithiolene) Molybdenum Complex that Promotes Combined Coupled Electron-Proton Transfer and Oxygen Atom Transfer Reactions: A Water-Active Model of the Arsenite Oxidase Molybdenum Center.
Sugimoto H, Tarumizu M, Miyake H, Tsukube H
Eur J Inorg Chem 2006 2006(22):4494-4497 [full text]
Selected by | Russ Hille
Evaluated 3 Jan 2007

Function and structure of the molybdenum cofactor carrier protein from Chlamydomonas reinhardtii.
Fischer K, Llamas A, …, Fernandez E, Schwarz G
J Biol Chem 2006 Oct 6 281(40):30186-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ruma Banerjee / Russ Hille
Evaluated 3 Jan 2007

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